Protein Alignment Prip and Aqp4

DIOPT Version :10

• Sequence 1: NP_001246266.1
• Gene: Prip / 36237
• FlyBaseID: FBgn0033635
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_001304658.1
• Gene: Aqp4 / 11829
• MGIID: 107387
• Length: 352
• Species: Mus musculus
• Alignment Length: 238
• Identity: 95/238 - (39%)
• Similarity: 132/238 - (55%)
• Gaps: 18/238 - (7%)

  Fly    21 WQALIGEFLGNLILNFFACGACTQIE----------DGTFKALAFGLAIFMAITIVGHLSGGHVN 75
            |:|:..|||..||  |...|..:.|.          |....:|.|||:|...:...||:||||:|
Mouse    35 WKAVSAEFLATLI--FVLLGVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCFGHISGGHIN 97

  Fly    76 PAVTAGMLVAGRISLIRAFFYVVFQCLGAIAGTAAVKILIDQDYYNGLGHTSLAPNITELQGLGI 140
            ||||..|:...:||:.::.||::.||||||.|...:.::.......|||.|::..|:|...||.:
Mouse    98 PAVTVAMVCTRKISIAKSVFYIIAQCLGAIIGAGILYLVTPPSVVGGLGVTTVHGNLTAGHGLLV 162

  Fly   141 EFFLGLLLVLVVFGACDPHKPDSRYTAPLAIGMAVTLGHLGTIRYTGASMNPARTVGTAFATDIW 205
            |..:...||..:|.:||..:.|...:..||||.:|.:|||..|.||||||||||:.|.|.....|
Mouse   163 ELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNW 227

  Fly   206 ASHWVYWVGPVLGGVAAALLYTQV----LEAKPVPKVNEASEK 244
            |:||:|||||::|.|.|..||..|    :|.|  .::.||..|
Mouse   228 ANHWIYWVGPIMGAVLAGALYEYVFCPDVELK--RRLKEAFSK 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prip	NP_001246266.1	MIP	12..226	CDD:444743	87/214 (41%)
Aqp4	NP_001304658.1	MIP	31..248	CDD:395174	87/214 (41%)