Protein Alignment Prip and Aqp2

DIOPT Version :9

• Sequence 1: NP_001246266.1
• Gene: Prip / 36237
• FlyBaseID: FBgn0033635
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_033829.3
• Gene: Aqp2 / 11827
• MGIID: 1096865
• Length: 271
• Species: Mus musculus
• Alignment Length: 269
• Identity: 98/269 - (36%)
• Similarity: 141/269 - (52%)
• Gaps: 22/269 - (8%)

  Fly    12 ELKSKELRLWQALIGEFLGNLILNFFACGACTQIEDGTFK----ALAFGLAIFMAITIVGHLSGG 72
            ||:|  :...:|::.|||..|:..||..|:..|.......    |:||||.|...:..:||:||.
Mouse     3 ELRS--IAFSRAVLAEFLATLLFVFFGLGSALQWASSPPSVLQIAVAFGLGIGTLVQALGHVSGA 65

  Fly    73 HVNPAVTAGMLVAGRISLIRAFFYVVFQCLGAIAGTAAVKILIDQDYYNGLGHTSLAPNITELQG 137
            |:|||||...||...:|.:||.|||..|.|||:||.|.:..:...:....|...:|..|.|..|.
Mouse    66 HINPAVTVACLVGCHVSFLRAAFYVAAQLLGAVAGAAILHEITPVEIRGDLAVNALHNNATAGQA 130

  Fly   138 LGIEFFLGLLLVLVVFGACDPHKPDSRYTAPLAIGMAVTLGHLGTIRYTGASMNPARTVGTAFAT 202
            :.:|.||.:.|||.:|.:.|..:.|:..:..|:||.:||||||..|.:||.||||||::..|..|
Mouse   131 VTVELFLTMQLVLCIFASTDERRSDNLGSPALSIGFSVTLGHLLGIYFTGCSMNPARSLAPAVVT 195

  Fly   203 DIWASHWVYWVGPVLGGVAAALLYTQVLEAKPVPKVNEASEKYR--------THADEREGCKPN- 258
            ..:..|||:|:||::|.|..:|||..:|    .|......|:..        |..:|||..:..
Mouse   196 GKFDDHWVFWIGPLVGAVIGSLLYNYLL----FPSTKSLQERLAVLKGLEPDTDWEEREVRRRQS 256

  Fly   259 ---HNPNHL 264
               |:|..|
Mouse   257 VELHSPQSL 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prip	NP_001246266.1	MIP	12..226	CDD:294134	86/217 (40%)
Aqp2	NP_033829.3	MIP	3..219	CDD:278651	86/217 (40%)
		NPA 1. /evidence=ECO:0000250|UniProtKB:P41181	68..70		1/1 (100%)
		NPA 2. /evidence=ECO:0000250|UniProtKB:P41181	184..186		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	251..271		3/15 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53729
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100198
Panther	1	1.100	-	-	O	PTHR19139
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	1	1.000	-	-		X83
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.860