Protein Alignment Prip and AQP7B

DIOPT Version :10

• Sequence 1: NP_001246266.1
• Gene: Prip / 36237
• FlyBaseID: FBgn0033635
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: XP_006712950.1
• Gene: AQP7B / 100509620
• HGNCID: 53895
• Length: 375
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 64/272 - (23%)
• Similarity: 108/272 - (39%)
• Gaps: 45/272 - (16%)

  Fly    17 ELRLWQALIGEFLGNLILNFFACGACT-QIEDGTFKA-----LAFGLAIFMAITIVGHLSGGHVN 75
            |.::.:..:.||:...::..|..|:.. .:.:.|:.:     |.||..:.|.:.:.|.:||.|:|
Human    63 ERKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKTYGSYLGVNLGFGFGVTMGVHVAGRISGAHMN 127

  Fly    76 PAVTAGMLVAGRISLIRAFFYVVFQCLGAIAGTAAVKILIDQDYYNGLGH--------------- 125
            .|||......||:...:...:|:.|.||:....|.:..|    :|..:.|
Human   128 AAVTFTNCALGRVPWRKFPVHVLGQFLGSFLAAATIYSL----FYTAILHFSGGELMVTGPFATA 188

  Fly   126 ----TSLAPNITELQGLGIEFFLGLLLVLVVFGACD-PHKPDSRYTAPLAIGMAVTLGHLGTIRY 185
                |.|..::|..:|...|.:|..:|.|.:|...| .:.|....|..|.|.:.|.:..:.....
Human   189 GIFATYLPDHMTLWRGFLNEEWLTRMLQLCLFTITDQENNPALPGTHALVISILVVIIRVSHGIN 253

  Fly   186 TGASMNPARTVGTAFATDI--WASH---------WVYWVGPVLGGVAAALLYTQVLEAKPVPKVN 239
            ||.::||:|....:..|.|  |...         ||..|.|:||.....::|. |.....:|:..
Human   254 TGYAINPSRDPPPSIFTFIAGWGKQVFSDGENWWWVPVVAPLLGASLGGIIYL-VFIGSTIPREP 317

  Fly   240 ---EASEKYRTH 248
               |.|..|..|
Human   318 LKLEDSVAYEDH 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prip	NP_001246266.1	MIP	12..226	CDD:444743	57/245 (23%)
AQP7B	XP_006712950.1	MIP	64..313	CDD:444743	58/253 (23%)