DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prip and aqp5

DIOPT Version :9

Sequence 1:	NP_001246266.1	Gene:	Prip / 36237	FlyBaseID:	FBgn0033635	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001297041.1	Gene:	aqp5 / 100491662	XenbaseID:	XB-GENE-479726	Length:	289	Species:	Xenopus tropicalis

Alignment Length:	259	Identity:	95/259 - (36%)
Similarity:	138/259 - (53%)	Gaps:	30/259 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LRLWQALIGEFLGNLILNFFACGAC----------TQIEDGTFKALAFGLAIFMAITIVGHLSGG 72
            |..|:|:..|||..||..||..|:.          .||      :|||||.|...:..|||:||.
Frog     8 LVFWKAIFAEFLATLIFVFFGLGSALRWPAALPTVLQI------SLAFGLVIGTLVQSVGHISGA 66

  Fly    73 HVNPAVTAGMLVAGRISLIRAFFYVVFQCLGAIAGTAAVKILIDQDYYNGLGHTSLAPNITELQG 137
            |:|||||...||..:|||||||||::.|.||.:||...:..::..:....|...:|:.|||....
Frog    67 HINPAVTMSFLVGSQISLIRAFFYIIAQLLGGLAGAGILYGVVSPNVRGNLAINTLSNNITPGVA 131

  Fly   138 LGIEFFLGLLLVLVVFGACDPHKPDSRYTAPLAIGMAVTLGHLGTIRYTGASMNPARTVGTAFAT 202
            ..:|..|...||:.:|.:.|..:.|:..:..|:||::||||||..|.:||.||||||:...|...
Frog   132 FVVEMILTFQLVMCIFASTDSRREDNVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFAPAVVV 196

  Fly   203 DIWASHWVYWVGPVLGGVAAALLYTQVLEAKPVPKVNEASEKY----------RTHADEREGCK 256
            ..:.:|||:|:||:.||:.|:|.|..:|    .|.....|:|.          .:.:|:::.||
Frog   197 RRFTNHWVFWIGPLAGGMLASLTYNYIL----FPSTKTRSQKLAILLGTYVEEESWSDQQDNCK 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prip	NP_001246266.1	MIP	12..226	CDD:294134	87/217 (40%)
aqp5	NP_001297041.1	MIP	4..220	CDD:333943	87/217 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53729
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19139
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X83
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.030