DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drip and Aqp9

DIOPT Version :9

Sequence 1:	NP_001260893.1	Gene:	Drip / 36236	FlyBaseID:	FBgn0015872	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_001258772.1	Gene:	Aqp9 / 64008	MGIID:	1891066	Length:	321	Species:	Mus musculus

Alignment Length:	235	Identity:	65/235 - (27%)
Similarity:	103/235 - (43%)	Gaps:	37/235 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 FLIFVGVGSTT--------SGSVPQIAFTFGLTVATIAQGLGHLSGCHINPAVTLGFLIVGEISI 91
            |.:.:|.||..        :|.:..|...|...|.........:||.||||||:......|.:..
Mouse    61 FYLVLGCGSIAQAVLSREKAGGIITINIGFATAVVMALYATFGVSGGHINPAVSFAMCTFGRMEW 125

  Fly    92 LKAAFYIIVQCVGAIAGAA-VIKVALDGV---AGGDLGVSSFD-----------PSLNCAQAVLI 141
            .|..||:..|.:||..||| |..:..||:   |.|.|.::..:           |.::...|.:.
Mouse   126 FKFPFYVGAQLLGAFVGAATVFGIYYDGLMAFADGKLLITGENGTAFIFATYPKPFVSVPGAFVD 190

  Fly   142 EALITFILVFVVKAVSDPGRQDI-KGSAPLAVGLAIAAGHLCAIKL-SGASMNPARSFGPAVVQG 204
            :.:.|..|:.:|.|:.|.....: :|..|:.:||.|.. ..|::.| ||.:|||||...|.:...
Mouse   191 QVVSTMFLLLIVFAIFDSRNLGVPRGLEPIVIGLLIIV-ISCSLGLNSGCAMNPARDLSPRLFTA 254

  Fly   205 V--W---------TYHWVYWVGPIAGGLLAGIIYRLIFKL 233
            :  |         .:.|:..|||:.|.:|.|:||.|..::
Mouse   255 LAGWGFEVFTFGNNFWWIPVVGPMIGAVLGGLIYVLFIQM 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drip	NP_001260893.1	MIP	23..227	CDD:294134	62/227 (27%)
Aqp9	NP_001258772.1	MIP	<61..292	CDD:294134	65/231 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830756
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53729
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.760