DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Drip and aqp3

DIOPT Version :9

Sequence 1:	NP_001260893.1	Gene:	Drip / 36236	FlyBaseID:	FBgn0015872	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_001016845.1	Gene:	aqp3 / 549599	XenbaseID:	XB-GENE-488014	Length:	294	Species:	Xenopus tropicalis

Alignment Length:	261	Identity:	74/261 - (28%)
Similarity:	107/261 - (40%)	Gaps:	39/261 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 KIWRMLLGELVGTFFLIFVGVGST-----TSGSVPQ-----IAFTFGLTVATIAQGLGHLSGCHI 75
            |:.|..|.|.:||..|:..|.||.     :.||..|     :||.|.:.:..:..  |.:||.|:
Frog    20 KLLRQALSECLGTLILVMFGCGSVAQVVLSKGSHGQFLTVNLAFGFAVMLGILIS--GQVSGGHL 82

  Fly    76 NPAVTLGFLIVGEISILKAAFYIIVQCVGAIAGAAVI-KVALDGV------------AGGDLGVS 127
            |||||....|:.....:|...|...|.:||..||.:| .:..|.:            ..|..|:.
Frog    83 NPAVTFALCIMAREPWIKFPIYSFAQTLGAFLGAGIIYGLYYDAIWFFGNDQLFVMGENGTAGIF 147

  Fly   128 SFDPS--LNCAQAVLIEALITFILVFVVKAVSDPGRQDI-KGSAPLAVGLAIAAGHLCAIKLSGA 189
            :..||  |........:.:.|..|:..|.|:.||....| :|.....||..:..........||.
Frog   148 TTFPSEHLTLINGFFDQFIGTAALIVCVLAIVDPNNNPIPRGLEAFTVGFVVLVIGTSMGFNSGY 212

  Fly   190 SMNPARSFGPAVVQGV--WTYHWVYWVG------PIAGGLLAGIIYRLIFKLKKGC--TPFQGHE 244
            ::||||.|||.:...:  |... |:|.|      ||...||......|:::|..||  .|.|..:
Frog   213 AVNPARDFGPRLFTSLAGWGTE-VFWAGNQWWWVPIVSPLLGAFTGVLVYQLMIGCHIEPAQTPQ 276

  Fly   245 S 245
            |
Frog   277 S 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drip	NP_001260893.1	MIP	23..227	CDD:294134	66/237 (28%)
aqp3	NP_001016845.1	MIP	24..264	CDD:238204	66/242 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53729
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930