DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drip and aqp2

DIOPT Version :9

Sequence 1:	NP_001260893.1	Gene:	Drip / 36236	FlyBaseID:	FBgn0015872	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_001015749.1	Gene:	aqp2 / 548466	XenbaseID:	XB-GENE-481401	Length:	273	Species:	Xenopus tropicalis

Alignment Length:	216	Identity:	101/216 - (46%)
Similarity:	136/216 - (62%)	Gaps:	12/216 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 RMLLGELVGTFFLIFVGVGSTTS--GSVP---QIAFTFGLTVATIAQGLGHLSGCHINPAVTLGF 83
            |.:..|.:.|...:|:|:||..|  .|:|   ||:..|||.::|:.|..||:||.|||||||:.|
Frog    12 RAVFAEFLATMIFVFLGMGSALSWKPSLPNVLQISLAFGLAISTLVQAFGHISGAHINPAVTIAF 76

  Fly    84 LIVGEISILKAAFYIIVQCVGAIAGAAVIKVALDGVAGGDLG---VSSFDPSLNCAQAVLIEALI 145
            ||...||.|:|.||||.|.||||||||::.......|.|:|.   |::..|...||    :|..:
Frog    77 LIGCHISFLRALFYIIAQLVGAIAGAAIVSAIAPLDARGNLAINEVTNGSPGQACA----VELFL 137

  Fly   146 TFILVFVVKAVSDPGRQDIKGSAPLAVGLAIAAGHLCAIKLSGASMNPARSFGPAVVQGVWTYHW 210
            ||.||..|.|.:|..|.|..||..:::||::..|||..|.|:|.|||||||||||.:.|::|.||
Frog   138 TFQLVLCVFASTDSRRSDNVGSPAISIGLSVTVGHLLGIYLTGCSMNPARSFGPAAITGIFTDHW 202

  Fly   211 VYWVGPIAGGLLAGIIYRLIF 231
            |:|:||:.||:||.:.|..||
Frog   203 VFWIGPLVGGILASLFYNYIF 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drip	NP_001260893.1	MIP	23..227	CDD:294134	98/210 (47%)
aqp2	NP_001015749.1	MIP	4..219	CDD:333943	98/210 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	1	1.000	-	-		X83
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.040