DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drip and aqp8a.1

DIOPT Version :9

Sequence 1:	NP_001260893.1	Gene:	Drip / 36236	FlyBaseID:	FBgn0015872	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_001004661.1	Gene:	aqp8a.1 / 447923	ZFINID:	ZDB-GENE-040912-106	Length:	260	Species:	Danio rerio

Alignment Length:	217	Identity:	82/217 - (37%)
Similarity:	118/217 - (54%)	Gaps:	10/217 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LGELVGTFFLIFVGVGST-----TSGSVPQIAFTFGLTVATIAQGLGHLSGCHINPAVTLGFLIV 86
            |.|:||:|..:|||..|.     .|||: |.|...||.:|......|.:||.|.||||::...::
Zfish    40 LAEVVGSFLFMFVGCVSVMGNVGISGSI-QPALAHGLALAIAIAIFGEISGGHFNPAVSVCVYLI 103

  Fly    87 GEISILKAAFYIIVQCVGAIAGAAVIKVALDGVAGGDLGVSSFD--PSLN-CAQAVLIEALITFI 148
            |.:.::....|||.|.:|.:..|::.|......|..:...::|:  ||.: ...|.:.|.::|..
Zfish   104 GGMEVILLVPYIISQMLGGVIAASLAKAVTTNDAFSNATGAAFNAIPSSDGIGAATMAEMIMTLF 168

  Fly   149 LVFVVKAVSDPGRQDIKGSAPLAVGLAIAAGHLCAIKLSGASMNPARSFGPAVVQGVWTYHWVYW 213
            |..||...:..||...: .||..:||.:.|..|....:|||.|||||:||||||.|.||:||:||
Zfish   169 LTIVVSMGAVNGRTKSQ-LAPFCIGLTVTANILAGGGISGACMNPARAFGPAVVSGHWTHHWIYW 232

  Fly   214 VGPIAGGLLAGIIYRLIFKLKK 235
            |||:.|.|:...|.||:...||
Zfish   233 VGPLTGALVTVSIVRLVMGDKK 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drip	NP_001260893.1	MIP	23..227	CDD:294134	77/207 (37%)
aqp8a.1	NP_001004661.1	MIP	39..249	CDD:294134	79/210 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53729
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100198
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	1	1.000	-	-		X83
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.760