Protein Alignment Drip and AQP7

DIOPT Version :9

• Sequence 1: NP_001260893.1
• Gene: Drip / 36236
• FlyBaseID: FBgn0015872
• Length: 278
• Species: Drosophila melanogaster
• Sequence 2: NP_001161.1
• Gene: AQP7 / 364
• HGNCID: 640
• Length: 342
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 71/269 - (26%)
• Similarity: 116/269 - (43%)
• Gaps: 46/269 - (17%)

  Fly     5 TEMSKFVG---VADITE--NKKIWRMLLGELVGTFFLIFVGVGSTTS-------GSVPQIAFTFG 57
            |..||.|.   :|.|.|  .:|:.|..|.|.:.|:.::..|:||...       ||...:...||
Human    11 TRGSKMVSWSVIAKIQEILQRKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFG 75

  Fly    58 LTVATIAQGLGHLSGCHINPAVTLGFLIVGEISILKAAFYIIVQCVGAIAGAAVI----KVALDG 118
            ..|.......|.:||.|:|.|||.....:|.:...|...|::.|.:|:...||.|    ..|:..
Human    76 FGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILH 140

  Fly   119 VAGGDLGV----------SSFDPS-LNCAQAVLIEALITFILVFVVKAVSD-PGRQDIKGSAPLA 171
            .:||.|.|          :::.|. :...:..|.||.:|.:|...:.|::| .....:.|:..|.
Human   141 FSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALV 205

  Fly   172 VGLAIAAGHLCAIKL---SGASMNPARSFGPAVVQGV--W---------TYHWVYWVGPIAGGLL 222
            :|:.:.   :..:.|   :|.::||:|...|.:...:  |         .:.||..|.|:.|..|
Human   206 IGILVV---IIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAYL 267

  Fly   223 AGIIYRLIF 231
            .|||| |:|
Human   268 GGIIY-LVF 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drip	NP_001260893.1	MIP	23..227	CDD:294134	59/240 (25%)
AQP7	NP_001161.1	MIP	31..280	CDD:412216	64/249 (26%)
		NPA 1. /evidence=ECO:0000250|UniProtKB:P55064	94..96		1/1 (100%)
		NPA 2. /evidence=ECO:0000250|UniProtKB:P55064	226..228		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53729
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850