Protein Alignment Drip and AQP1

DIOPT Version :9

• Sequence 1: NP_001260893.1
• Gene: Drip / 36236
• FlyBaseID: FBgn0015872
• Length: 278
• Species: Drosophila melanogaster
• Sequence 2: NP_001316801.1
• Gene: AQP1 / 358
• HGNCID: 633
• Length: 323
• Species: Homo sapiens
• Alignment Length: 225
• Identity: 95/225 - (42%)
• Similarity: 135/225 - (60%)
• Gaps: 12/225 - (5%)

  Fly    18 ENKKIWRMLLGELVGTFFLIFVGVGSTTSGSVP------------QIAFTFGLTVATIAQGLGHL 70
            :.|..||.::.|.:.|...:|:.:||......|            :::..|||::||:||.:||:
Human     6 KKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGHI 70

  Fly    71 SGCHINPAVTLGFLIVGEISILKAAFYIIVQCVGAIAGAAVIKVALDGVAGGDLGVSSFDPSLNC 135
            ||.|:|||||||.|:..:|||.:|..|||.||||||...|::......:.|..||.:.....:|.
Human    71 SGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRNDLADGVNS 135

  Fly   136 AQAVLIEALITFILVFVVKAVSDPGRQDIKGSAPLAVGLAIAAGHLCAIKLSGASMNPARSFGPA 200
            .|.:.||.:.|..||..|.|.:|..|:|:.||||||:||::|.|||.||..:|..:|||||||.|
Human   136 GQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSA 200

  Fly   201 VVQGVWTYHWVYWVGPIAGGLLAGIIYRLI 230
            |:...::.||::||||..||.||.:||..|
Human   201 VITHNFSNHWIFWVGPFIGGALAVLIYDFI 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drip	NP_001260893.1	MIP	23..227	CDD:294134	91/215 (42%)
AQP1	NP_001316801.1	NPA 1	76..78		1/1 (100%)
		NPA 2	192..194		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	190	1.000	Domainoid score	I3263
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I3838
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53729
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	1	1.000	-	-		otm41396
orthoMCL	1	0.900	-	-		OOG6_100198
Panther	1	1.100	-	-	O	PTHR19139
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	1	1.000	-	-		X83
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	12	11.910