DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drip and aqp1a.1

DIOPT Version :9

Sequence 1:	NP_001260893.1	Gene:	Drip / 36236	FlyBaseID:	FBgn0015872	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_996942.1	Gene:	aqp1a.1 / 335821	ZFINID:	ZDB-GENE-030131-7764	Length:	260	Species:	Danio rerio

Alignment Length:	218	Identity:	100/218 - (45%)
Similarity:	143/218 - (65%)	Gaps:	12/218 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 ENKKIWRMLLGELVGTFFLIFV----GVGSTTSGSVPQ---IAFTFGLTVATIAQGLGHLSGCHI 75
            ::|..||.:|.||:|....||:    .||:|.:.:..|   :|..|||::||:||.|||:||.|:
Zfish     5 KSKAFWRAVLAELLGMTLFIFLSITAAVGNTNTQNPDQEIKVALAFGLSIATLAQSLGHISGAHL 69

  Fly    76 NPAVTLGFLIVGEISILKAAFYIIVQCVGAIAGAAVIKVALDGVAGGD-LGVSSFDPSLNCAQAV 139
            |||||||.|...:||:|:|..||:.|.:||...:|::.    ||:.|| ||::.....::..|.|
Zfish    70 NPAVTLGLLASCQISLLRAVMYILAQMIGATVASAIVL----GVSKGDALGLNQIHTDISAGQGV 130

  Fly   140 LIEALITFILVFVVKAVSDPGRQDIKGSAPLAVGLAIAAGHLCAIKLSGASMNPARSFGPAVVQG 204
            .||.|.||.||..|.|.:|..|:|:.||||||:||::..|||.||..:|..:||||:||||:::.
Zfish   131 GIELLATFQLVLCVLATTDKRRRDVSGSAPLAIGLSVCLGHLTAISFTGCGINPARTFGPAMIRL 195

  Fly   205 VWTYHWVYWVGPIAGGLLAGIIY 227
            .:..||||||||:.||:.|.:||
Zfish   196 DFANHWVYWVGPMCGGVAAALIY 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drip	NP_001260893.1	MIP	23..227	CDD:294134	97/211 (46%)
aqp1a.1	NP_996942.1	MIP	3..218	CDD:278651	98/216 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	206	1.000	Domainoid score	I2854
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53729
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	1	1.000	-	-		otm25039
orthoMCL	1	0.900	-	-		OOG6_100198
Panther	1	1.100	-	-	O	PTHR19139
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	1	1.000	-	-		X83
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.860