DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drip and Aqp6

DIOPT Version :9

Sequence 1:	NP_001260893.1	Gene:	Drip / 36236	FlyBaseID:	FBgn0015872	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_071517.1	Gene:	Aqp6 / 29170	RGDID:	71100	Length:	276	Species:	Rattus norvegicus

Alignment Length:	218	Identity:	91/218 - (41%)
Similarity:	119/218 - (54%)	Gaps:	11/218 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 IW----RMLLGELVGTFFLIFVGVGS-----TTSGSVPQIAFTFGLTVATIAQGLGHLSGCHINP 77
            :|    :.|..|.:.|...:|.||||     ....||.|:|.||.|..||..|.....||.|.||
  Rat    16 LWTAISKALFAEFLATGLYVFFGVGSVLPWPVALPSVLQVAITFNLATATAVQISWKTSGAHANP 80

  Fly    78 AVTLGFLIVGEISILKAAFYIIVQCVGAIAGAAVIKVALDGVAGGDLGVSSFDPSLNCAQAVLIE 142
            ||||.:|:...||:.:|..||..|..||..|||::.....|.....|||:....|.:..|||.:|
  Rat    81 AVTLAYLVGSHISLPRAVAYIAAQLAGATVGAALLYGVTPGGVRETLGVNVVHNSTSTGQAVAVE 145

  Fly   143 ALITFILVFVVKAVSDPGRQDIKGSAPLAVGLAIAAGHLCAIKLSGASMNPARSFGPAVVQGVWT 207
            .::|..||..|.|..| .||.: ||....:|.::|.|||..|..:|.||||||||||||:.|.:.
  Rat   146 LVLTLQLVLCVFASMD-SRQTL-GSPAAMIGTSVALGHLIGIYFTGCSMNPARSFGPAVIVGKFA 208

  Fly   208 YHWVYWVGPIAGGLLAGIIYRLI 230
            .||::||||:.|.:||.:||..|
  Rat   209 VHWIFWVGPLTGAVLASLIYNFI 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drip	NP_001260893.1	MIP	23..227	CDD:294134	88/212 (42%)
Aqp6	NP_071517.1	MIP	22..228	CDD:294134	87/207 (42%)
		NPA 1	79..81		1/1 (100%)
		NPA 2	193..195		1/1 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334481
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53729
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	1	1.000	-	-		otm45514
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19139
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X83
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.960