DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drip and aqp-5

DIOPT Version :9

Sequence 1:	NP_001260893.1	Gene:	Drip / 36236	FlyBaseID:	FBgn0015872	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_505691.2	Gene:	aqp-5 / 183221	WormBaseID:	WBGene00000173	Length:	316	Species:	Caenorhabditis elegans

Alignment Length:	266	Identity:	61/266 - (22%)
Similarity:	103/266 - (38%)	Gaps:	71/266 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 ELVGTFFLIFVGVGSTTSGSVPQIAFTFGLTVATIAQGL---------GHLSGCHINPAVTLGFL 84
            |.:|||..||.|   |...:|..|:...|||.|.:..||         |.:||.|.||.|:...:
Worm    49 EFLGTFIFIFSG---TMQANVYDISQPVGLTHAALTHGLATIVVIAVFGKISGGHFNPVVSWAMV 110

  Fly    85 IVGEISILKAAFYIIVQCVGAIAG---------------------------AAVIKVALDGVAGG 122
            :..::...:..||:..|..|..||                           .|.|:...|.|...
Worm   111 LCQKLHPFELPFYMFSQFFGGFAGNLLSACLQRKRDFLNWEDYSSIRYPLPTASIEYGYDKVHNS 175

  Fly   123 DL---------------GVSSFDPSLNCAQAVLIEALIT--FILVFVVKAVSDPGRQDIKGSAPL 170
            .|               |::....:....:.::.|.:.|  |:.|.::..|::...:    :.|.
Worm   176 TLEKTILLTTQLAATTSGITHLGENHEWWEGLISETITTYFFVTVILMNVVNNEPSE----ATPF 236

  Fly   171 AVGLAIAAGHLCAIKLSGASMNPARSFGPAVVQGV-----------WTYHWVYWVGPIAGGLLAG 224
            .:|:.:.........::|.:|||.|:..|.:|..:           ||||::||.||..|..:|.
Worm   237 IIGMMVIVNIFATASITGTAMNPVRALSPNIVGEIVLSSSSLPPNFWTYHYIYWAGPYLGSTIAV 301

  Fly   225 IIYRLI 230
            |.::|:
Worm   302 IGFKLL 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drip	NP_001260893.1	MIP	23..227	CDD:294134	60/261 (23%)
aqp-5	NP_505691.2	MIP	45..307	CDD:294134	60/264 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	121	1.000	Domainoid score	I3512
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	125	1.000	Inparanoid score	I3275
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53729
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	1	1.000	-	-		FOG0000054
OrthoInspector	1	1.000	-	-		mtm4734
orthoMCL	1	0.900	-	-		OOG6_100198
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X83
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.780