DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drip and Aqp7

DIOPT Version :9

Sequence 1:	NP_001260893.1	Gene:	Drip / 36236	FlyBaseID:	FBgn0015872	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_001365567.1	Gene:	Aqp7 / 11832	MGIID:	1314647	Length:	316	Species:	Mus musculus

Alignment Length:	203	Identity:	54/203 - (26%)
Similarity:	92/203 - (45%)	Gaps:	23/203 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 KKIWRMLLGELVGTFFLIFVGVGST-------TSGSVPQIAFTFGLTVATIAQGLGHLSGCHINP 77
            |.:.|..|.|.:.|:.::..|:||.       .|||...:...||..|.......|.:||.|:|.
Mouse    16 KNMVREFLAEFLSTYVMMVFGLGSVAHMVLGENSGSYLGVNLGFGFGVTMGVHVAGGISGAHMNA 80

  Fly    78 AVTLGFLIVGEISILKAAFYIIVQCVGAIAGAA----VIKVALDGVAGGDLGVSSFDPSLNCA-- 136
            |||.....:|.::..|...|::.|.:|:.:.||    :...|::..|||||.|:....:.|..
Mouse    81 AVTFTNCALGRMTWKKFPVYVLGQFLGSFSAAATTYLIFYGAINHFAGGDLLVTGSKATANIFAT 145

  Fly   137 ---------QAVLIEALITFILVFVVKAVSDPGRQD-IKGSAPLAVGLAIAAGHLCAIKLSGASM 191
                     :..|.||.:|.:|...:.|::|..... ::|:.||.:|:.:....:.....||.::
Mouse   146 YLPEYMTLWRGFLDEAFVTGMLQLCLFAITDKKNSPALQGTEPLVIGILVTVLGVSLGMNSGYAI 210

  Fly   192 NPARSFGP 199
            ||:|...|
Mouse   211 NPSRDLPP 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drip	NP_001260893.1	MIP	23..227	CDD:294134	53/200 (27%)
Aqp7	NP_001365567.1	MIP	18..232	CDD:412216	53/201 (26%)
		NPA 1	79..81		1/1 (100%)
		NPA 2	211..213		1/1 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53729
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850