DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7763 and COLEC12

DIOPT Version :9

Sequence 1:	NP_001356891.1	Gene:	CG7763 / 36235	FlyBaseID:	FBgn0040503	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_569057.2	Gene:	COLEC12 / 81035	HGNCID:	16016	Length:	742	Species:	Homo sapiens

Alignment Length:	166	Identity:	41/166 - (24%)
Similarity:	68/166 - (40%)	Gaps:	27/166 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 GTSTNLQLENQNTSQQLLTHGTAMGRKLEENEI---FQQLGSKYYYIEKEEKLNWHDALDKCHKM 137
            |....|.|:|:.|...            |:|..   ::....|.||...|::: :.||...|...
Human   587 GAVVPLALQNEPTPAP------------EDNGCPPHWKNFTDKCYYFSVEKEI-FEDAKLFCEDK 638

  Fly   138 GGHLASLQSQEELDRFNNQLNGLNRYWIDVTNQFNESEFVSVTKGSKANFLSWADGEPTKDG--- 199
            ..||..:.::||......|:.|...:||.:|:...|:|: ....|:..::.:|..|:|...|
Human   639 SSHLVFINTREEQQWIKKQMVGRESHWIGLTDSERENEW-KWLDGTSPDYKNWKAGQPDNWGHGH 702

  Fly   200 ----ECVDIRTFNGKTTMNDNSCFANLYFICEKSIE 231
                :|..: .:.|:  .||..|.....|||||..|
Human   703 GPGEDCAGL-IYAGQ--WNDFQCEDVNNFICEKDRE 735

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7763	NP_001356891.1	CLECT	116..228	CDD:153057	30/118 (25%)
COLEC12	NP_569057.2	SMC_N	<77..350	CDD:330553
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	439..608		7/32 (22%)
		CLECT_DC-SIGN_like	607..732	CDD:153060	31/129 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910