DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7763 and CLEC11A

DIOPT Version :9

Sequence 1:	NP_001356891.1	Gene:	CG7763 / 36235	FlyBaseID:	FBgn0040503	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_002966.1	Gene:	CLEC11A / 6320	HGNCID:	10576	Length:	323	Species:	Homo sapiens

Alignment Length:	230	Identity:	52/230 - (22%)
Similarity:	84/230 - (36%)	Gaps:	55/230 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 YCYGVLNPCIASMGNLQRRVEACEAAVAIARIALNDRRLDNFGTSTN-----LQLENQNTSQQLL 93
            |..|.|....|.:..|..|:.|.:..|  ..:....|:|.|....|.     || |.|..:::
Human   110 YILGRLAGLDAGLHQLHVRLHALDTRV--VELTQGLRQLRNAAGDTRDAVQALQ-EAQGRAER-- 169

  Fly    94 THGTAMGRKLEENEIFQQLGSKYYYIEKEEKLNWHDALDKCHKMGGHLASLQSQEELDRFNNQLN 158
            .||     :||......:||.|.:.:.::.:.. ..|..:|...||.||     :..||  .|:.
Human   170 EHG-----RLEGCLKGLRLGHKCFLLSRDFEAQ-AAAQARCTARGGSLA-----QPADR--QQME 221

  Fly   159 GLNRY------------WIDVTNQFNESEFVSVTKGSKANFLSW-------ADGEPTKDGECVDI 204
            .|.||            |:.|.::..|..:: ...|.:.:|.:|       ...:|:.....:..
Human   222 ALTRYLRAALAPYNWPVWLGVHDRRAEGLYL-FENGQRVSFFAWHRSPRPELGAQPSASPHPLSP 285

  Fly   205 RTFNGKTTMN------------DNSCFANLYFICE 227
            ...||.|..|            |:.|...||::||
Human   286 DQPNGGTLENCVAQASDDGSWWDHDCQRRLYYVCE 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7763	NP_001356891.1	CLECT	116..228	CDD:153057	29/143 (20%)
CLEC11A	NP_002966.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	55..106
		Cell attachment site. /evidence=ECO:0000255	61..63
		CLECT_tetranectin_like	177..321	CDD:153066	32/153 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	272..295		4/22 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I11773
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	55	1.000	Inparanoid score	I5435
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.960