DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7763 and Clec4a

DIOPT Version :9

Sequence 1:	NP_001356891.1	Gene:	CG7763 / 36235	FlyBaseID:	FBgn0040503	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_001005899.2	Gene:	Clec4a / 474143	RGDID:	1359662	Length:	240	Species:	Rattus norvegicus

Alignment Length:	132	Identity:	40/132 - (30%)
Similarity:	62/132 - (46%)	Gaps:	10/132 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 FQQLGSKYYYIEKE----EKLNWHDALDKCHKMGGHLASLQSQEELDRFNNQLNGLNRYWIDVTN 169
            ::..||..|::.|.    .|.:|:::...|..||.||..:.|:||.|.....||....|:|.:.:
  Rat   111 WKPFGSHCYWVTKHTSTYSKASWNESEKNCFSMGAHLLVIHSKEEQDFITGILNRDAAYFIGLWD 175

  Fly   170 Q-FNESEFVSVTK-GSKANFLSWADGEPTKDGE-CVDIRTFNGKTTMNDNSCFANLYFICE-KSI 230
            . ..:.::||.|. .:.|.|  |..|||:.|.| ||.|...|.....||..|......:|: |.|
  Rat   176 SGHRQWQWVSQTPYNASATF--WHKGEPSSDDEKCVIINHLNSGWGWNDIPCSGKQQSVCQMKKI 238

  Fly   231 EI 232
            ::
  Rat   239 QL 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7763	NP_001356891.1	CLECT	116..228	CDD:153057	36/119 (30%)
Clec4a	NP_001005899.2	ITIM motif	5..10
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	18..38
		CLECT_DC-SIGN_like	107..235	CDD:153060	38/125 (30%)
		Mannose binding. /evidence=ECO:0000250\|UniProtKB:Q9UMR7	200..202		1/1 (100%)
		N-acetyl-D-glucosamine binding. /evidence=ECO:0000250\|UniProtKB:Q9UMR7	211..213		1/1 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I11467
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	57	1.000	Inparanoid score	I5325
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22802
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.060