DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7763 and MRC1

DIOPT Version :9

Sequence 1:	NP_001356891.1	Gene:	CG7763 / 36235	FlyBaseID:	FBgn0040503	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_002429.1	Gene:	MRC1 / 4360	HGNCID:	7228	Length:	1456	Species:	Homo sapiens

Alignment Length:	234	Identity:	59/234 - (25%)
Similarity:	101/234 - (43%)	Gaps:	43/234 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LSSSYSAACEGVE-SDSQCAAY---CYGVLNPCIASMGNLQRRVEACEAAVAIARIALND---RR 71
            |..:|.:..||.. ||....:|   .||..|       |.| .||.|........::.||   ..
Human   715 LGLTYGSPSEGFTWSDGSPVSYENWAYGEPN-------NYQ-NVEYCGELKGDPTMSWNDINCEH 771

  Fly    72 LDNFGTSTNLQLENQNTSQQLLTHGTAMGRKLEENEIFQQLGSKYYYIEKEEKLNWHDALDKCHK 136
            |:|:    ..|::...|.:...|........:.|:........:||:.:::|.::  :|...|.:
Human   772 LNNW----ICQIQKGQTPKPEPTPAPQDNPPVTEDGWVIYKDYQYYFSKEKETMD--NARAFCKR 830

  Fly   137 MGGHLASLQSQEE---LDRFNNQLNGLNRYWIDVTNQFNESEFVSVTK------GSKANFLSWAD 192
            ..|.|.|:||:.|   |.::.|:.:..:.|:|.:        .:|:.|      |||.:::|||.
Human   831 NFGDLVSIQSESEKKFLWKYVNRNDAQSAYFIGL--------LISLDKKFAWMDGSKVDYVSWAT 887

  Fly   193 GEP---TKDGECVDIRTFNGKTTMNDNSCFANLYFICEK 228
            |||   .:|..||.:.:.:|  ..||.:|.....|||::
Human   888 GEPNFANEDENCVTMYSNSG--FWNDINCGYPNAFICQR 924

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7763	NP_001356891.1	CLECT	116..228	CDD:153057	36/123 (29%)
MRC1	NP_002429.1	RICIN	27..142	CDD:214672
		RICIN	34..141	CDD:238092
		FN2	161..209	CDD:128373
		CLECT	234..342	CDD:153057
		CLECT	362..487	CDD:214480
		CLECT	504..626	CDD:214480
		CLECT	659..779	CDD:153057	19/75 (25%)
		CLECT	802..923	CDD:214480	35/132 (27%)
		CLECT	945..1080	CDD:214480
		CLECT	1097..1213	CDD:214480
		CLECT	1230..1356	CDD:214480
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910