DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7763 and Vcan

DIOPT Version :9

Sequence 1:	NP_001356891.1	Gene:	CG7763 / 36235	FlyBaseID:	FBgn0040503	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_001074718.1	Gene:	Vcan / 13003	MGIID:	102889	Length:	3354	Species:	Mus musculus

Alignment Length:	240	Identity:	58/240 - (24%)
Similarity:	86/240 - (35%)	Gaps:	70/240 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 CLS--------SSYSAACEGVESDSQCAA---YCYGVLNPCIASMGNLQRRVEACEAAVAIARIA 66
            ||:        :||...|....|..||..   .|:.  |||        |....|
Mouse  3056 CLNGGTCYPTETSYVCTCAPGYSGDQCELDFDECHS--NPC--------RNGATC---------- 3100

  Fly    67 LNDRRLDNFGTSTNLQLENQNTSQQLLTHGTAMGRKLEEN--------EIFQQLGSKYYYIEKEE 123
                 :|.|.|...|.|.:.            :|...|::        ..||....||:    ..
Mouse  3101 -----VDGFNTFRCLCLPSY------------VGALCEQDTETCDYGWHKFQGQCYKYF----AH 3144

  Fly   124 KLNWHDALDKCHKMGGHLASLQSQEELDRFNNQLNGLNRYWIDVTNQFNESEFVSVTKGSKANFL 188
            :..|..|..:|...|.||.|:.|.|| ..|.|:: |.:..||.:.::..|.:| ..|.||...:.
Mouse  3145 RRTWDAAERECRLQGAHLTSILSHEE-QMFVNRV-GHDYQWIGLNDKMFEHDF-RWTDGSALQYE 3206

  Fly   189 SWADGEP----TKDGECVDIRTF-NGKTTMNDNSCFANLYFICEK 228
            :|...:|    :...:||.|... ||:  .||..|..:|.:.|:|
Mouse  3207 NWRPNQPDSFFSAGEDCVVIIWHENGQ--WNDVPCNYHLTYTCKK 3249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7763	NP_001356891.1	CLECT	116..228	CDD:153057	33/116 (28%)
Vcan	NP_001074718.1	IG_like	29..147	CDD:214653
		Ig_Versican	36..151	CDD:143309
		Link_domain_CSPGs_modules_1_3	150..244	CDD:239594
		Link_domain_CSPGs_modules_2_4	251..346	CDD:239597
		GAG-alpha (glucosaminoglycan attachment domain)	348..1308
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	625..646
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	801..863
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	881..908
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1010..1088
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1252..1288
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1396..1421
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1458..1524
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1924..1963
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2471..2490
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2849..2904
		EGF_CA	3049..3083	CDD:238011	7/26 (27%)
		EGF_CA	3085..3121	CDD:238011	12/72 (17%)
		CLECT_CSPGs	3127..3250	CDD:153058	37/132 (28%)
		CCP	3254..3310	CDD:153056
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910