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Protein Alignment Smyd4-3 and SMYD2

DIOPT Version :9

Sequence 1:	NP_725048.1	Gene:	Smyd4-3 / 36234	FlyBaseID:	FBgn0033633	Length:	660	Species:	Drosophila melanogaster
Sequence 2:	NP_064582.2	Gene:	SMYD2 / 56950	HGNCID:	20982	Length:	433	Species:	Homo sapiens

Alignment Length:	467	Identity:	109/467 - (23%)
Similarity:	186/467 - (39%)	Gaps:	131/467 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   236 FVSPLVRIDSNRQEGRFARASADVKPGEELLVERPFVSVLLEKFAKTHCENCFMRTVVPVACPRC 300
            |.||        .:||..||....:.|:.|.....:..||.......|||.||.|......|.||
Human    12 FCSP--------GKGRGLRALQPFQVGDLLFSCPAYAYVLTVNERGNHCEYCFTRKEGLSKCGRC 68

  Fly   301 ADVLYCSEQCREEASKKYHKYECGIVPII-----WRSGASINNHIALRIIASKPLDYFLKLKPTI 360
            ....||:.:|::| ....||.||.  |::     |....::  .:..||:|          |..|
Human    69 KQAFYCNVECQKE-DWPMHKLECS--PMVVFGENWNPSETV--RLTARILA----------KQKI 118

  Fly   361 DEELTP-EQLISLPKDDFRRVAQLERH--QGERQPSNFFQHVLMA--RFLTNCLRAGGYFGSEPK 420
            ..|.|| |:|::        |.:.|.|  :.:.:..:..|..:.|  .|.:..|   |:
Human   119 HPERTPSEKLLA--------VKEFESHLDKLDNEKKDLIQSDIAALHHFYSKHL---GF------ 166

  Fly   421 PDEVSIICSLVLRSLQFIQFNTHEVAELHKFSSSGREKSIFIGGAIYPTLALFNHSCDPGVVRYF 485
            ||..|::       :.|.|.|      .:.|:....|.| .:|.||:|.:||.||||.|.|:..:
Human   167 PDNDSLV-------VLFAQVN------CNGFTIEDEELS-HLGSAIFPDVALMNHSCCPNVIVTY 217

  Fly   486 RGTTIHINSVRPIEAGLPINENY-GPMYTQDERSERQARLKDLYWFECSCDAC------------ 537
            :||...:.:|:.|:.|..:..:| ..:|..::|::   ||:|.|:|.|.|..|
Human   218 KGTLAEVRAVQEIKPGEEVFTSYIDLLYPTEDRND---RLRDSYFFTCECQECTTKDKDKAKVEI 279

  Fly   538 --IDNWPKFDDLPRDVIRF---------RCDAPNNCSAVIEVPPSCNDFMVKCVTCGEITNI--- 588
              :.:.||.:.: ||::|:         |.....:.|.::|:   |.....|..:..|.:|:
Human   280 RKLSDPPKAEAI-RDMVRYARNVIEEFRRAKHYKSPSELLEI---CELSQEKMSSVFEDSNVYML 340

  Fly   589 ---LKGLKV---MQDTEMMTRTAKRLYE--TGEYPKALAKFVDLIRIMYEVLAPPFPDFCESQQH 645
               .:.:.|   |||.|...:..:::.:  :..||            :|.:             :
Human   341 HMMYQAMGVCLYMQDWEGALQYGQKIIKPYSKHYP------------LYSL-------------N 380

  Fly   646 LKDCFLNLGNVY 657
            :...:|.||.:|
Human   381 VASMWLKLGRLY 392

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.