DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Smyd4-3 and SmydA-7

DIOPT Version :9

Sequence 1:	NP_725048.1	Gene:	Smyd4-3 / 36234	FlyBaseID:	FBgn0033633	Length:	660	Species:	Drosophila melanogaster
Sequence 2:	NP_001261039.1	Gene:	SmydA-7 / 36916	FlyBaseID:	FBgn0034182	Length:	488	Species:	Drosophila melanogaster

Alignment Length:	302	Identity:	72/302 - (23%)
Similarity:	115/302 - (38%)	Gaps:	60/302 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   250 GRFARASADVKPGEELLVERPFVSVLLEKFAKTHCENCFMRTVVPVACPRCADVLYCSEQCREEA 314
            ||...||..::||:.:|.|||.:.....:..:..|..|...:.  |.|.||.....|.: |.:
  Fly    17 GRHLVASIAIEPGDTILEERPLLVAPHWECHQLKCAQCLQESY--VICRRCQVFPLCMD-CNQ-- 76

  Fly   315 SKKYHKYECGIVPIIWRSGA--SINNHIALRIIASKPLDYFLKLKPTIDEELTP---EQLISLP- 373
               :.::||.    .:.|||  ::...|   ::.:..:...|||...::...|.   :.||.:|
  Fly    77 ---HDEFECE----FFTSGAGKALCKDI---LVKNFGICGLLKLLLLLENPRTKGDCQMLIDVPI 131

  Fly   374 -KDDFRRVAQLERHQGE---RQPSNFFQHVLMARFLTNCLRAGGYFGSEPKPDEVSIICSLVLRS 434
             ..|:|        .||   ::........||...|.:.|..     .|...|.:...|   :|
  Fly   132 NLSDYR--------DGEGMWQEHEELVVRPLMESGLADVLPT-----QELTSDALHAHC---IR- 179

  Fly   435 LQFIQFNTHEVAELHKFSSSGREKSIFIGGAIYPTLALFNHSCDPG-VVRYFRGTTIHINSVRPI 498
               |..|:.||..    ......|.||:.||..|      |.|.|. ||.......:.:.:..|:
  Fly   180 ---IDSNSFEVTA----KDGDTLKGIFVWGATLP------HHCVPNTVVALDEQFNMKLYAAVPL 231

  Fly   499 EAGLPINENY-GPMYTQDERSERQARLKDLYWFECSCDACID 539
            :.|..|..:| .|:.   ..|:||.:|:.....||.|..|:|
  Fly   232 QPGDIIYNSYTNPLM---GTSQRQHQLRLSRRLECICSRCLD 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-3	NP_725048.1	TPR_11	74..143	CDD:290150
		TPR repeat	74..103	CDD:276809
		TPR repeat	108..142	CDD:276809
		TPR repeat	150..177	CDD:276809
		zf-MYND	284..323	CDD:280009	8/38 (21%)
SmydA-7	NP_001261039.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810