Protein Alignment Smyd4-3 and Smyd4-4

DIOPT Version :9

• Sequence 1: NP_725048.1
• Gene: Smyd4-3 / 36234
• FlyBaseID: FBgn0033633
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: NP_610730.1
• Gene: Smyd4-4 / 36299
• FlyBaseID: FBgn0027495
• Length: 573
• Species: Drosophila melanogaster
• Alignment Length: 612
• Identity: 149/612 - (24%)
• Similarity: 247/612 - (40%)
• Gaps: 119/612 - (19%)

  Fly    33 KLSACKSDEERVAYVEK----LPWVQAGDANLVVNQEFAGKNASLAAEIKERATSAF--KAKKWL 91
            |.:..|.:..:|.:|.:    ..:::....|:.:.::...|.   :.|.:......|  |.:.:.
  Fly    26 KFNELKENHRKVDFVMRALIDFKYIEKIFLNVTLREDKCNKR---SVEFRMLGNEQFSLKNRNYF 87

  Fly    92 EAMMLYTRSYVALPSENVAEIRVVLANRSATLYHMQKYQECLIDIKRALDLSYSKDLIYKLYERQ 156
            :|:.||.:| :.....|...:.:..|||||.|:..::|::||.:||.|...:|...|.:||.:|:
  Fly    88 QALELYNKS-ICYAEPNSEHLSIGYANRSAVLFEWKRYRQCLDNIKLARQANYPARLSHKLDKRE 151

  Fly   157 ARCYMALKDYPHTIDSFKKCITAMDDSTLASDKRAKLNLDAMTMIKMLQNDPRTAKQEAKQQKQK 221
            ..|...|...|..:..::                .||:.:....:
  Fly   152 RDCQQLLDQQPPDVVPYE----------------FKLSFEPHAQV-------------------- 180

  Fly   222 IALDQAKPVKLENEFVSPLVRIDSNRQEGRFARASADVKPGEELLVERPFVSVLLEKFAKTHCEN 286
                         .|::..:.:.....||||...:.|:..|:.:.||.||.|.||.......|..
  Fly   181 -------------PFIADCLELRETAAEGRFVVTNRDLAVGDLVSVEEPFCSTLLTPMRYIRCAT 232

  Fly   287 CFMR---TVVPVACPRCADVLYCSEQCREEASKKYHKYECGIVPIIWRSGASINNHIALR--IIA 346
            |...   |::|  |..|...::|||:|:..|.:.||:|||.|:..:.|....| :.||||  ::|
  Fly   233 CKRENYLTLIP--CDSCCSTMFCSEECKSIAMQTYHRYECPIIDFLNRMFNKI-HCIALRTTLVA 294

  Fly   347 SKPLDYFLKLKPTID-----------------EELTPEQLISLPKDDFRRVAQLERHQGERQPSN 394
               |:.|..::..||                 .|||||       :.:|.:..|..:|..|..|:
  Fly   295 ---LNIFPSIEELIDFCEQEQNQDKCAFDLNYNELTPE-------EHYRAIHGLVTNQHLRSVSD 349

  Fly   395 FFQH----VLMARFLTNCLRAGGYFGSEPKPDEVSIICSLVLRSLQFIQFNTHEVAELHKFSSSG 455
            .||.    .::..|:........|.|.|   :.|:....|:.|.||....|.|.: :|.:..:..
  Fly   350 LFQRSVVCAVLKHFIIEYTPVKEYLGGE---EGVNFFTDLLFRHLQTSPSNMHGI-DLVEQVNET 410

  Fly   456 REKSIFIGGAIYPTLALFNHSCDPGVVRYFRGTTIHINSVRPIEAGLPINENYGPMYTQDERSER 520
            ::......|| |..|:|.||||.|..||.:.||..::..:|||:||..:.:|||..:....:.:|
  Fly   411 KDDQTHSSGA-YAFLSLINHSCAPNTVRIYEGTKAYMFVLRPIKAGNVLYDNYGAHFAICSKEQR 474

  Fly   521 QARLKDLYWFECSCDACIDNWPKFDDLPR--------DVIRFRCDAPNNCSAVIEVPPSCNDFMV 577
            ..||...|.|:|.|:.|..|:|.|..:|.        |.......:.|...||......| ||:.
  Fly   475 LKRLSLQYRFDCKCEGCELNYPMFGMMPHKATVPSVTDDTELALSSYNYDFAVSNYRKYC-DFLT 538

  Fly   578 K------CVTCGEITNILK-GLKVMQD 597
            :      |.........|| .|.:|.|
  Fly   539 QYGDDYPCEQISSAEECLKMALHIMAD 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-3	NP_725048.1	TPR_11	74..143	CDD:290150	20/70 (29%)
		TPR repeat	74..103	CDD:276809	7/30 (23%)
		TPR repeat	108..142	CDD:276809	13/33 (39%)
		TPR repeat	150..177	CDD:276809	6/26 (23%)
		zf-MYND	284..323	CDD:280009	14/41 (34%)
Smyd4-4	NP_610730.1	TPR_11	67..138	CDD:290150	20/74 (27%)
		zf-MYND	230..270	CDD:280009	14/41 (34%)
		SET	363..463	CDD:279228	32/104 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	61	1.000	Domainoid score	I3824
eggNOG	1	0.900	-	-		E2759_KOG2084
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	64	1.000	Inparanoid score	I3964
Isobase	1	0.950	-	0	Normalized mean entropy	S6581
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1278034at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26456
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.820