Protein Alignment Smyd4-3 and LOC3291277

DIOPT Version :10

• Sequence 1: NP_725048.1
• Gene: Smyd4-3 / 36234
• FlyBaseID: FBgn0033633
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: XP_564258.2
• Gene: LOC3291277 / 3291277
• VectorBaseID: AGAMI1_001411
• Length: 1309
• Species: Anopheles gambiae
• Alignment Length: 616
• Identity: 143/616 - (23%)
• Similarity: 238/616 - (38%)
• Gaps: 161/616 - (26%)

  Fly    69 KNASLAAEIKERATSAF--KAKKWLEAMMLYTRSYVALPSENVAEIR-VVLANRSATLYHMQKYQ 130
            |:.:.|...::|....|  ...|:||::..|..|...  ||..:|.| :...|||.....:...|
Mosquito    69 KDNAKALAARKRGNELFVPMQGKYLESLQHYNESIAY--SEPGSEARALAYGNRSVVCLKLGLSQ 131

  Fly   131 ECLIDIKRALDLSYSKDLIYKLYERQARCYMALKDYPHTIDSFKKCITAMDDSTLASDKRAKLNL 195
            |||.:|:.|...:|...|:.||.:|:              ...|:||
Mosquito   132 ECLENIRLARASNYPARLMNKLNKRE--------------QDVKRCI------------------ 164

  Fly   196 DAMTMIKMLQNDPRTAKQEAKQQKQKI-ALDQAKPV-KLENE------FVSPLVRIDSNRQEGRF 252
                     :||.:...:.......|. |.:...|| :|..|      .::..|.:..|.|.||.
Mosquito   165 ---------ENDAQIIPRRVTHTPGKYWARETGCPVLQLSYEAHANIPHLAKCVELRQNSQYGRH 220

  Fly   253 ARASADVKPGEELLVERPFVSVL--LEKFAK-THCENCFMRTVVPVACPRCADVLYCSEQCREEA 314
            ...:..:|.|:..|:|:|:.::|  .|::.: ..|:|....|::|  |..|...:|||::|.::|
Mosquito   221 LVTTQHLKAGDVFLIEKPYANLLCDTERYKRCAFCQNEDTFTLIP--CEGCTVAMYCSKECMDKA 283

  Fly   315 SKKYHKYECGIVPIIWR-SGASINNHIALRIIAS------KPLDYFLKLKPTIDE---------- 362
            .|:||:||||::...|| .|......:.||.:|:      :.|:.::....|:||
Mosquito   284 HKQYHRYECGVLRDCWRIVGHLFGGMVGLRTVATAIASFDQDLEGWIDHLNTLDEANVNAFTVDW 348

  Fly   363 -ELTPEQLISLPKDDFRRVAQLERHQGERQPSN--FFQHVLMARFLTN------CLRAGGYFGSE 418
             |:|...:.    |....:|..::.:|.:..|.  ||..::....|..      |         |
Mosquito   349 NEVTDSDMY----DTVHVLATNQKRRGRKDLSKLIFFTSIVHLLLLERTELGPLC---------E 400

  Fly   419 PKPDEVSIICSLVLRSLQFIQFNTHEV--------------------------AELHKFSSSGRE 457
            ..|....::..|:||.:|....|...|                          .|..:::..|.|
Mosquito   401 SNPARSKLLFDLLLRHVQTSLINKKGVYHMTRSKDDEEDDEYEDNYFGYDRDDEEEQEYTDYGEE 465

  Fly   458 KSIFIGGAIYPTLALFNHSCDPGV--VRYFRGTTIHINSVRPIEAGLPINENYGPMYTQDERSER 520
            ....   |:||..::.||||.|.|  :....|....:.: |||.||..:.:.|..:..:.:.|.|
Mosquito   466 THAI---AVYPLFSMVNHSCIPNVAPIHLLDGRCAFVAN-RPIAAGEQLFDVYDFLTMEFDPSFR 526

  Fly   521 QARLKDLYWFECSCDACIDNWPKFDDLPRDVIRFRCDAPNNCSAVIEVPPSCNDFMVKCVTCGEI 585
            :..||..|:|.|.|.||...||    :|     ||     |.|...|      .|:   :...|:
Mosquito   527 RYCLKQSYFFNCRCPACQSGWP----MP-----FR-----NKSLAEE------HFL---LLLREM 568

  Fly   586 TNILKGLKVMQDTEMMTRTAKRLYETGEYPK 616
            .|:::||..:  .|.|.:..:      .|||
Mosquito   569 DNVVQGLPRL--VEYMNQAGR------HYPK 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-3	NP_725048.1	TPR repeat	74..103	CDD:276809	8/30 (27%)
		TPR repeat	108..142	CDD:276809	11/34 (32%)
		TPR repeat	150..177	CDD:276809	4/26 (15%)
		SET_SMYD4	235..537	CDD:380934	86/364 (24%)
		zf-MYND	284..323	CDD:460312	15/38 (39%)
LOC3291277	XP_564258.2	None