Protein Alignment Smyd4-3 and LOC3289638

DIOPT Version :10

• Sequence 1: NP_725048.1
• Gene: Smyd4-3 / 36234
• FlyBaseID: FBgn0033633
• Length: 660
• Species: Drosophila melanogaster
• Sequence 2: XP_566179.1
• Gene: LOC3289638 / 3289638
• VectorBaseID: AGAMI1_014221
• Length: 526
• Species: Anopheles gambiae
• Alignment Length: 531
• Identity: 130/531 - (24%)
• Similarity: 220/531 - (41%)
• Gaps: 116/531 - (21%)

  Fly    54 QAGDANLVVNQEFAGKNASLAAE--IKERATSAFKAKKWLEAMMLYTRSYVALPSENVAEIRVVL 116
            :||...|:|:    ||:...|||  ::..|......|::::|:.||.:| :|..::...|.....
Mosquito     7 RAGQQGLLVD----GKDNRKAAELCVEGNAMHYNNVKRYMDAVKLYNKS-IAYSTKGSPERAQAY 66

  Fly   117 ANRSATLYHMQKYQECLIDIKRALDLSYSKDLIYKLYERQARCYMALKDYPHTIDSFKKCITAMD 181
            ..||.....:.:|.:|..:::.|.| |....|:.:..:...||..::            .::|.|
Mosquito    67 WERSKVCVKLNQYADCQQNLRLARD-SDGPGLLRRKLDESERCARSM------------LLSATD 118

  Fly   182 DSTLASDKRA----KLNLDAMTMIKMLQNDPRTAKQEAKQQKQKIALDQAKPVKLENEFVSPLVR 242
            |:|..|.:..    ||:..|      .:|.||.|.          .|:..:         ||
Mosquito   119 DATPGSSRHGAAPLKLSFPA------YENAPRVAN----------CLEMRR---------SP--- 155

  Fly   243 IDSNRQEGRFARASADVKPGEELLVERPFVSVLLEKFAKTHCENC-----FMRTVVPVACPRCAD 302
                 |.||:.:.:..:|.|:.::::.|:||||..:|....|::|     |  |::|  |.||..
Mosquito   156 -----QYGRYLQTNKALKVGDVVMIDEPYVSVLEPEFCYARCDHCQRPAPF--TLIP--CERCTK 211

  Fly   303 VLYCSEQCREEASKKYHKYECGIV---------PII---WRSGASI--------------NNHIA 341
            .:|||:.|...|..:||::||.:|         |::   ||:....              .|:::
Mosquito   212 AMYCSKNCLRRARTEYHEFECALVHHLTETTRDPVVLLAWRAVTRAISTYRYNLRHLKQRRNYLS 276

  Fly   342 LRIIASKPLDYFLKLKPTIDEELTPEQLISLPKDDFR-RVAQLERHQGERQPSNFFQHVLMARFL 405
            ...:....|::....|...........|...|.|... ||||:.|.          .|..:..
Mosquito   277 RTEVNPLMLNWVDGQKIAFSAVYILASLARAPNDPVEARVAQISRE----------MHCHLVS-- 329

  Fly   406 TNCLRAGGYFGSEPKPDEVSIICSLVLRSLQFIQFNTHEVAELHKFSSSGREKSIFIGGAIYPTL 470
            .|...|....||.|.| .|..:|   .|.|:.:|.|........:....|:.:::......:|.:
Mosquito   330 ENGQTANDDSGSVPYP-WVGEMC---YRFLKVMQCNARPAQLTRRDEPEGQYRAVPFALRCHPLI 390

  Fly   471 ALFNHSCDPGV----VRYFRGTTIHINSVRPIEAGLPINENYGPMYTQDERSERQARLKDLYWFE 531
            :|.||||.|.|    :|..|.:.:   .::||.||..:..|||..|.|..|.||:..|:.::.|.
Mosquito   391 SLLNHSCAPNVKCFDLRDGRCSAV---VIQPIAAGGQLFANYGYDYLQTGRDERREGLQRVFGFT 452

  Fly   532 CSCDACIDNWP 542
            |:||||.:|:|
Mosquito   453 CNCDACENNYP 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-3	NP_725048.1	TPR repeat	74..103	CDD:276809	9/30 (30%)
		TPR repeat	108..142	CDD:276809	6/33 (18%)
		TPR repeat	150..177	CDD:276809	2/26 (8%)
		SET_SMYD4	235..537	CDD:380934	86/337 (26%)
		zf-MYND	284..323	CDD:460312	15/43 (35%)
LOC3289638	XP_566179.1	SET	143..458	CDD:394802	90/364 (25%)