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Protein Alignment Smyd4-3 and Smyd4

DIOPT Version :9

Sequence 1:	NP_725048.1	Gene:	Smyd4-3 / 36234	FlyBaseID:	FBgn0033633	Length:	660	Species:	Drosophila melanogaster
Sequence 2:	NP_001096081.1	Gene:	Smyd4 / 319822	MGIID:	2442796	Length:	799	Species:	Mus musculus

Alignment Length:	673	Identity:	155/673 - (23%)
Similarity:	260/673 - (38%)	Gaps:	130/673 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 KERATSAFKAKKWLEAMMLYTRSYVALPSENVAEIRVVLANRSATLYHMQKYQECLIDIKRALDL 142
            :|.....|:.|::.:|.:||::. |:....|..:|.:..|||||.|:|:.:|:.||.||..|...
Mouse    72 REEGNRKFQEKEYTDAAVLYSKG-VSHSRPNTEDISLCYANRSAALFHLGQYEACLKDIVEAGMH 135

  Fly   143 SYSKDLIYKLYERQARCYM---ALKDYPHTIDSFKKCITAMDDSTLASDKRAKLNLDAMTMIKML 204
            .|.:.|..|:..|:..|.:   .|::...||...:..:||.....|:|             .::|
Mouse   136 GYPERLQPKMMVRKTECLVNLGRLQEARQTISDLESSLTAKPTLVLSS-------------YQIL 187

  Fly   205 QNDPRTAKQEAKQQKQKIALDQAKPVKLENEF--------------VSPLVRIDSNRQEGRFARA 255
            |.:.:..|.:.   ::|..|.:..|..|.|.|              .|..|.:.::..:||...|
Mouse   188 QRNVQHLKIKI---QEKETLPEPIPAALTNAFEDIALGEENTQISGASLSVSLCTHPLKGRHLVA 249

  Fly   256 SADVKPGEELLVERPFVSVLLE-KFAKTH-----------------CENCFMRTVVPVACPRCAD 302
            :.|:.|||.|:.|..|||||:. :..:.|                 |..|...|:..|.|..|:.
Mouse   250 TKDILPGELLVKEDAFVSVLIPGEMPRPHHCLENKWDTRVTSGDLYCHRCLKHTLATVPCGSCSY 314

  Fly   303 VLYCSEQCREEASKKYHKYECGIVPIIWRSGASINNHIALRI-------------------IAS- 347
            ..|||::|.::|...||..||.:..::...|  :..|:|||:                   :.|
Mouse   315 AKYCSQECMQQAWDLYHSTECSLGGLLLTLG--VFCHVALRMTLLARFEDVDRVVRMLCDEVGST 377

  Fly   348 -----------KPLDYFLKLKPTIDEELTPEQLISLPK-----------DDFRRVAQLERHQGER 390
                       |..||      |...|...:..|..|.           .::..:..|..|..:.
Mouse   378 DTCLPESKNLVKAFDY------TSQGESEEKSKIGEPPIPGCNVNGKYGSNYNAIFSLLPHTEKH 436

  Fly   391 QPSNFFQHVLMARFLTNCLRAGGYFGSEPKPDEVSII----C-------SLVLRSLQFIQFNTHE 444
            .|.:.|...:....|...|:|........|..::..:    |       :.:||.:..:|.|...
Mouse   437 SPEHRFICAISVSALCRQLKADSVQAQTLKSPKLKAVTPGLCADLTVWGAAMLRHMLQLQCNAQA 501

  Fly   445 VAEL-HKFSSSG---REKSIFIGGAIYPTLALFNHSCDPGVVRYFRGTTIHINSVRPIEAGLPIN 505
            :..: |..|:..   ..:.|.:...|:|.::|.||||.|.....|.||...:.:.:.|..|..|.
Mouse   502 ITSICHTGSNESIITNSRQIRLATGIFPVVSLLNHSCRPNTSVSFTGTVATVRAAQRIAKGQEIL 566

  Fly   506 ENYGPMYTQDERSERQARLKDLYWFECSCDACIDNWPKFDDLPRDVIRFRCDAPNNCSAVI---E 567
            ..|||..::...:|||.||...|:|:|.|.||.....:....|| ...|.|   ..|.|::   :
Mouse   567 HCYGPHESRMGVAERQQRLSSQYFFDCRCGACHAETLRAAAAPR-WEAFCC---KTCRALMQGND 627

  Fly   568 VPPSCNDFMVKCVTCGEITNILKGLKVMQDTEMMTRTAKRLYETGEYPKALAKFVDLIRIMYEVL 632
            |....|:.....|:..::.:.|      ||.:.....|::|..||:..:|:.:.:.........|
Mouse   628 VLSCSNESCTNSVSRDQLVSRL------QDLQQQVCMAQKLLRTGKPEQAIQQLLRCREAAESFL 686

  Fly   633 APPFPDFCESQQHLKDCFLNLGN 655
            :.......|.:..|......|||
Mouse   687 SAEHTVLGEIEDGLAQAHATLGN 709

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.