DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Smyd4-3 and SmydA-9

DIOPT Version :9

Sequence 1:	NP_725048.1	Gene:	Smyd4-3 / 36234	FlyBaseID:	FBgn0033633	Length:	660	Species:	Drosophila melanogaster
Sequence 2:	NP_001285040.1	Gene:	SmydA-9 / 31859	FlyBaseID:	FBgn0030102	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	360	Identity:	75/360 - (20%)
Similarity:	121/360 - (33%)	Gaps:	77/360 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   239 PLVRIDSNRQEGRFARASADVKPGEELLVERPFVSVLL--EKFAKTHCENCF-MRTVVPVACPRC 300
            |...|..::..||...|:..:|.||.:..:.|.:..|.  |:.:...|..|. |.......|.:.
  Fly    23 PAWEIGVSKIAGRGVVATRSLKRGEIIFRDSPLLIGLAAHEEDSLNACSVCLKMLPDTRFMCRQG 87

  Fly   301 ADVLYCSEQCREEASKKYHKYECGIVPIIWRSGASINNHIALRIIASKPLDYFLKLKPTIDEELT 365
            ..:..|| .|   |.||.||.:|.:......:...:.|.:.:|:                   |.
  Fly    88 CGLPVCS-LC---AKKKQHKSDCDLFKSWGPNEPDVANSVIIRL-------------------LC 129

  Fly   366 PEQLISLPKDDFRRVAQLERHQGERQPSNFFQHVLMARFLTNCLRAGGYFGSEPKPDEVSIICSL 430
            ..:.|:|.|:....:..|:.:...       .|....|....|.:   .|.::.|..|:......
  Fly   130 VARAINLSKEQRDLIYCLQANLDN-------NHRTEVRNAAKCFK---NFPTDKKLIEIMNRTVA 184

  Fly   431 VLRSLQFIQFNTHEVAELHKFSSSGREKSIFIGGAIYPTLALFNHSCDPGVVRYFRGTT--IHIN 493
            |||:..|           .|.:....:...|...|:||...:.||.|.|.....|...|  :.:.
  Fly   185 VLRTNGF-----------DKTTDRTNDNQEFNYRALYPLFGVVNHDCIPNAYYTFEEKTNNMIVR 238

  Fly   494 SVRPIEAGLPINENYGPMYTQDERSERQARLKDLYWFECSCDACIDNWPKFDDLP----RDVIRF 554
            :...|..|..:...|..::|.:  ..|...||....|.|.|..|.|...|...:.    ||
  Fly   239 AAVDIPEGFEVTTTYTKLFTGN--IARHLFLKMKKSFTCKCSRCSDPTEKGAFISGLYCRD---- 297

  Fly   555 RCDAPNNCSAVIEVP-------PSCNDFMVKCVTC 582
                 .||:.:: ||       |:.|     |:.|
  Fly   298 -----TNCTGLV-VPEITGLPHPNWN-----CLVC 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-3	NP_725048.1	TPR_11	74..143	CDD:290150
		TPR repeat	74..103	CDD:276809
		TPR repeat	108..142	CDD:276809
		TPR repeat	150..177	CDD:276809
		zf-MYND	284..323	CDD:280009	12/39 (31%)
SmydA-9	NP_001285040.1	SET	25..>66	CDD:295368	10/40 (25%)
SmydA-9	NP_001285040.1	SET	<216..253	CDD:279228	8/36 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810