DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Smyd4-3 and Zmynd15

DIOPT Version :9

Sequence 1:	NP_725048.1	Gene:	Smyd4-3 / 36234	FlyBaseID:	FBgn0033633	Length:	660	Species:	Drosophila melanogaster
Sequence 2:	NP_001099270.1	Gene:	Zmynd15 / 287457	RGDID:	1309845	Length:	738	Species:	Rattus norvegicus

Alignment Length:	212	Identity:	43/212 - (20%)
Similarity:	66/212 - (31%)	Gaps:	85/212 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 AKQEAKQQKQKIALDQAKPVKLE-----NEFVSPLVRIDSNRQEGRFARASADVKPGEELLVER- 269
            |:.|...:|:|....:|.|:.|.     .:....::.||. ..:|  |:.|....||.|.|..|
  Rat   179 AEDERAPEKRKGRKTEAAPLHLSCLLLVTDEHGTILGIDL-LMDG--AQGSVGQSPGTENLAPRA 240

  Fly   270 --------------------------------------PFVSVLLEK-------------FAKTH 283
                                                  |.:.|.|.|             ||...
  Rat   241 YALLCHSMACPMGSGDPRKPRQLTVGDAHLHRELESLVPRLGVKLAKTPMRTWGPRPGFTFASLR 305

  Fly   284 CENC-------FMRTVVPVACPRCADVLYCSEQCREEASKK-----YHKYEC-GIVPIIWRSGAS 335
            ...|       |...:.|  ||:|:.||||.|.|.:...::     .|::.| .:...:.|:|.
  Rat   306 ARTCHVCHKHSFEVKLTP--CPQCSAVLYCGEACLQADWRRCPDDVSHRFWCPRLAAFMERAGE- 367

  Fly   336 INNHIALRIIASKPLDY 352
                     :||.|..|
  Rat   368 ---------LASLPFTY 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-3	NP_725048.1	TPR_11	74..143	CDD:290150
		TPR repeat	74..103	CDD:276809
		TPR repeat	108..142	CDD:276809
		TPR repeat	150..177	CDD:276809
		zf-MYND	284..323	CDD:280009	13/50 (26%)
Zmynd15	NP_001099270.1	zf-MYND	309..355	CDD:280009	13/47 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900