Protein Alignment Tsp47F and CD81

DIOPT Version :10

• Sequence 1: NP_725044.1
• Gene: Tsp47F / 36230
• FlyBaseID: FBgn0033629
• Length: 239
• Species: Drosophila melanogaster
• Sequence 2: XP_054226604.1
• Gene: CD81 / 975
• HGNCID: 1701
• Length: 335
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 72/271 - (26%)
• Similarity: 109/271 - (40%)
• Gaps: 71/271 - (26%)

  Fly     2 RSCGPSLIKYVLFAFNVLFAISGLGIL-------------IAGAVVLADVNEFNH--------FV 45
            ||...||:|           :..||:.             :||.|:|.......|        ::
Human    93 RSSSRSLLK-----------VGELGMAPFVHARAGKTKAQLAGGVILGVALWLRHDPQTTNLLYL 146

  Fly    46 E-GRVLAPP------IVLIVTGLIIFLIASLGCFGAIKESPTLLITFAVLLAVIFIVELAVGIAA 103
            | |...||.      .:||..|.::..:..|||:|||:||..||.||...|.::|..|:|.||..
Human   147 ELGDKPAPNTFYVGIYILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWG 211

  Fly   104 SVFK----KDLEGMVKNSLQESIKRSNSEDTMA-WDNIQQKLMCCGVDSPADWRTLSANKT--LP 161
            .|.|    ||::.....:||:::...::.:..| .....:.|.|||..      ||:|..|  |.
Human   212 FVNKDQIAKDVKQFYDQALQQAVVDDDANNAKAVVKTFHETLDCCGSS------TLTALTTSVLK 270

  Fly   162 GSCCQPQYIDSTVGHCLESPALGKDKYFQVGCVGKLKDRIEKNAIILIG-----VGIGIAFIQIL 221
            .:.|..       |..:.|      ..|:..|..|:.| :....:.|||     |.:.:.|..||
Human   271 NNLCPS-------GSNIIS------NLFKEDCHQKIDD-LFSGKLYLIGIAAIVVAVIMIFEMIL 321

  Fly   222 GIVLACYLANS 232
            .:||.|.:.||
Human   322 SMVLCCGIRNS 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp47F	NP_725044.1	Tetraspanin	9..231	CDD:459767	66/261 (25%)
		tetraspanin_LEL	<134..205	CDD:351888	16/72 (22%)
CD81	XP_054226604.1	Tetraspanin	122..327	CDD:459767	62/224 (28%)