Protein Alignment Tsp47F and CD53

DIOPT Version :10

• Sequence 1: NP_725044.1
• Gene: Tsp47F / 36230
• FlyBaseID: FBgn0033629
• Length: 239
• Species: Drosophila melanogaster
• Sequence 2: NP_000551.1
• Gene: CD53 / 963
• HGNCID: 1686
• Length: 219
• Species: Homo sapiens
• Alignment Length: 227
• Identity: 72/227 - (31%)
• Similarity: 112/227 - (49%)
• Gaps: 33/227 - (14%)

  Fly     8 LIKYVLFAFNVLFAISGLGILIAGAVVLADVNEFN---HFVEGRVLAPPIVLIVTGLIIFLIASL 69
            |:|||||.||:||.|.|..||..|..:|.. |.|.   |.:....|..  |.::.|.||.::|.|
Human     8 LLKYVLFFFNLLFWICGCCILGFGIYLLIH-NNFGVLFHNLPSLTLGN--VFVIVGSIIMVVAFL 69

  Fly    70 GCFGAIKESPTLLITFAVLLAVIFIVELAVGIAASVFKKDLEGMVKNSLQESIKRSNSEDT--MA 132
            ||.|:|||:..||::|.:||.:|.:.|:.:.|...|:::.|...|...|.:||.|.:|:::  .|
Human    70 GCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLTDSIHRYHSDNSTKAA 134

  Fly   133 WDNIQQKLMCCGVDSPADWRTLSANKTLPGSCCQPQYIDSTVGHCLESPALGKDKYFQVGCVGKL 197
            ||:||..|.|||::..:||     ....|.||...:.::                    ||..|.
Human   135 WDSIQSFLQCCGINGTSDW-----TSGPPASCPSDRKVE--------------------GCYAKA 174

  Fly   198 KDRIEKNAIILIGVGIGIAFIQILGIVLACYL 229
            :.....|.:.:..:.|.:..|::||:..|..|
Human   175 RLWFHSNFLYIGIITICVCVIEVLGMSFALTL 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp47F	NP_725044.1	Tetraspanin	9..231	CDD:459767	71/226 (31%)
		tetraspanin_LEL	<134..205	CDD:351888	15/70 (21%)
CD53	NP_000551.1	Tetraspanin	9..208	CDD:459767	71/226 (31%)
		CD53_like_LEL	104..186	CDD:239417	26/106 (25%)