Protein Alignment Tsp47F and CD37

DIOPT Version :10

• Sequence 1: NP_725044.1
• Gene: Tsp47F / 36230
• FlyBaseID: FBgn0033629
• Length: 239
• Species: Drosophila melanogaster
• Sequence 2: XP_005259492.1
• Gene: CD37 / 951
• HGNCID: 1666
• Length: 365
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 81/272 - (29%)
• Similarity: 127/272 - (46%)
• Gaps: 50/272 - (18%)

  Fly     7 SLIKYVLFAFNVLFAISGLGILIAGAVVLADVNEFNHFVEGRVLAP----PIVLIVTGLIIFLIA 67
            |||||.||.||:.|.:.|..|...|..:|.|...|..|| |....|    ..||.::|:....||
Human     9 SLIKYFLFVFNLFFFVLGSLIFCFGIWILIDKTSFVSFV-GLAFVPLQIWSKVLAISGIFTMGIA 72

  Fly    68 SLGCFGAIKESPTLLITFAVLLAVIFIVELAVGIAASVFKKDLEGMVKNSLQESIKR--SNSEDT 130
            .|||.||:||...||..:..:|.::|..::.:||..|..:..||..:::.::::|::  :|.|:|
Human    73 LLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLERSLRDVVEKTIQKYGTNPEET 137

  Fly   131 MA---WDNIQQKLMCCGVDSPADWRTL-------SANKTLPGSCCQ---------------PQYI 170
            .|   ||.:|.:|.|||...|.||..:       |....:|.||..               ||.
Human   138 AAEESWDYVQFQLRCCGWHYPQDWFQVLILRGNGSEAHRVPCSCYNLSATNDSTILDKVILPQL- 201

  Fly   171 DSTVGHCLES---------PALGKDKYFQVGCVGKLKDRIEKNAIILIGVGIGIAFIQILGIVLA 226
             |.:||...|         ||  :...::.||...|:..:..|.|.::|:.:|:..:::..:||:
Human   202 -SRLGHLARSRHSADICAVPA--ESHIYREGCAQGLQKWLHNNLISIVGICLGVGLLEMTVMVLS 263

  Fly   227 CYLANSIRQERA 238
            ..|     |.||
Human   264 VQL-----QRRA 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp47F	NP_725044.1	Tetraspanin	9..231	CDD:459767	76/261 (29%)
		tetraspanin_LEL	<134..205	CDD:351888	24/101 (24%)
CD37	XP_005259492.1	Tetraspanin	26..266	CDD:459767	67/244 (27%)
		CD37_CD82_like_LEL	108..243	CDD:239413	34/138 (25%)