Protein Alignment Tsp47F and CD9

DIOPT Version :10

• Sequence 1: NP_725044.1
• Gene: Tsp47F / 36230
• FlyBaseID: FBgn0033629
• Length: 239
• Species: Drosophila melanogaster
• Sequence 2: NP_001400170.1
• Gene: CD9 / 928
• HGNCID: 1709
• Length: 255
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 66/274 - (24%)
• Similarity: 108/274 - (39%)
• Gaps: 68/274 - (24%)

  Fly     5 GPSLIKYVLFAFNVLFAISGLGI--------------------LIAGAVVLA------------- 36
            |...|||:||.||.:|.:..|.:                    ::||..|||
Human     6 GTKCIKYLLFGFNFIFWLKSLRVPERKAGRSGAPLFGPRPRRTVLAGIAVLAIGLWLRFDSQTKS 70

  Fly    37 ----DVNEFN-HFVEGRVLAPPIVLIVTGLIIFLIASLGCFGAIKESPTLLITFAVLLAVIFIVE 96
                :.|..| .|..|     ..:||..|.::.|:..|||.||::||..:|..|...|.|||.:|
Human    71 IFEQETNNNNSSFYTG-----VYILIGAGALMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIE 130

  Fly    97 LAVGIAASVFKKDLEGMVKNSLQESIKRSNSEDTMAWDN---IQQKLMCCGVDSPADWRTLSANK 158
            :|..|.....|.::...|:...:::..:..::|....:.   |...|.|||:....:
Human   131 IAAAIWGYSHKDEVIKEVQEFYKDTYNKLKTKDEPQRETLKAIHYALNCCGLAGGVE-------- 187

  Fly   159 TLPGSCCQPQYIDSTVGHCLESPALGKDKYFQVGCVGKLKDRIEKNAIILIGVGIGIAFIQILGI 223
                     |:|...   |.:...|  :.:....|...:|:..:....|:..||||||.:.|.|:
Human   188 ---------QFISDI---CPKKDVL--ETFTVKSCPDAIKEVFDNKFHIIGAVGIGIAVVMIFGM 238

  Fly   224 VLACYLANSIRQER 237
            :.:..|..:||:.|
Human   239 IFSMILCCAIRRNR 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp47F	NP_725044.1	Tetraspanin	9..231	CDD:459767	62/262 (24%)
		tetraspanin_LEL	<134..205	CDD:351888	11/73 (15%)
CD9	NP_001400170.1	Tetraspanin	10..246	CDD:459767	62/262 (24%)
		CD9_LEL	138..220	CDD:239405	14/103 (14%)