Protein Alignment Tsp47F and TSPAN18

DIOPT Version :10

• Sequence 1: NP_725044.1
• Gene: Tsp47F / 36230
• FlyBaseID: FBgn0033629
• Length: 239
• Species: Drosophila melanogaster
• Sequence 2: XP_005253274.1
• Gene: TSPAN18 / 90139
• HGNCID: 20660
• Length: 258
• Species: Homo sapiens
• Alignment Length: 247
• Identity: 67/247 - (27%)
• Similarity: 121/247 - (48%)
• Gaps: 24/247 - (9%)

  Fly     7 SLIKYVLFAFNVLFAISGLGILIAGAVVLADVNEFNHFVEGR--VLAPPIVLIVTGLIIFLIASL 69
            |.:||::|.||....:.|..:|..|..|:.|...|...|...  :|....:|:..|.::||:..|
Human    17 SCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGLLFLLGFL 81

  Fly    70 GCFGAIKESPTLLITFAVLLAVIFIVELAVGIAASVFKKDL--EGMVKNSLQESIKRSNSEDTMA 132
            ||.||::|:..||:.|.:.:.:||:.||:..|.|.:|:::|  |...| .|.:..:.:|..|..:
Human    82 GCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTK-ELTKHYQGNNDTDVFS 145

  Fly   133 --WDNIQQKLMCCGVDSPADWRTLSA-------NKTLPGSCC--QPQYIDSTV---GHCLESPAL 183
              |:::.....||||:.|.|::..|.       ::.:|.:||  :||..|..:   ..||    |
Human   146 ATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQSRDGVLLSREECL----L 206

  Fly   184 GKDKYF-QVGCVGKLKDRIEKNAIILIGVGIGIAFIQILGIVLACYLANSIR 234
            |:..:. :.||...:.:..|....:...:.||:..|::..::.|..|...|:
Human   207 GRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMCLFRGIQ 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp47F	NP_725044.1	Tetraspanin	9..231	CDD:459767	65/240 (27%)
		tetraspanin_LEL	<134..205	CDD:351888	20/83 (24%)
TSPAN18	XP_005253274.1	Tetraspanin	20..255	CDD:459767	65/239 (27%)
		uroplakin_I_like_LEL	115..228	CDD:239409	29/117 (25%)