Protein Alignment Tsp47F and UPK1B

DIOPT Version :10

• Sequence 1: NP_725044.1
• Gene: Tsp47F / 36230
• FlyBaseID: FBgn0033629
• Length: 239
• Species: Drosophila melanogaster
• Sequence 2: NP_008883.2
• Gene: UPK1B / 7348
• HGNCID: 12578
• Length: 260
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 57/249 - (22%)
• Similarity: 99/249 - (39%)
• Gaps: 64/249 - (25%)

  Fly    26 GILIAGAVV-----LADVNEFNHFVEGRVLAPPI--------------VLIVTGLIIFLIASLGC 71
            |:||.|.|:     :|...|...||..:....|:              :.|..|:.:|.::.||.
Human    13 GLLIFGNVIIGCCGIALTAECIFFVSDQHSLYPLLEATDNDDIYGAAWIGIFVGICLFCLSVLGI 77

  Fly    72 FGAIKESPTLLITFAVLLAVIFIVELAVGIAASV----------FKKDLEGMVKNSLQESIKRSN 126
            .|.:|.|..:|:.:.:|:.:::..|:|..|.|:.          .|:.||....||      ..|
Human    78 VGIMKSSRKILLAYFILMFIVYAFEVASCITAATQQDFFTPNLFLKQMLERYQNNS------PPN 136

  Fly   127 SED-------TMAWDNIQQKLMCCGVDSPADWRTLS---------ANKTLPGSCCQPQYIDSTVG 175
            ::|       |..||.:..:..||||:.|:||:..:         |:...|..||....:...:.
Human   137 NDDQWKNNGVTKTWDRLMLQDNCCGVNGPSDWQKYTSAFRTENNDADYPWPRQCCVMNNLKEPLN 201

  Fly   176 HCLESPALG-KDKYFQVGCVGKLKDRIEKNAIILIGVGIGIAFIQILGIVLACY 228
              ||:..|| ...|...||...:...:.::|       .|:|:   .|..:.|:
Human   202 --LEACKLGVPGFYHNQGCYELISGPMNRHA-------WGVAW---FGFAILCW 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp47F	NP_725044.1	Tetraspanin	9..231	CDD:459767	57/249 (23%)
		tetraspanin_LEL	<134..205	CDD:351888	19/80 (24%)
UPK1B	NP_008883.2	Tetraspanin	14..>161	CDD:459767	34/152 (22%)
		uroplakin_I_like_LEL	118..230	CDD:239409	28/119 (24%)