Protein Alignment Tsp47F and TSPAN4

DIOPT Version :10

• Sequence 1: NP_725044.1
• Gene: Tsp47F / 36230
• FlyBaseID: FBgn0033629
• Length: 239
• Species: Drosophila melanogaster
• Sequence 2: NP_001426622.1
• Gene: TSPAN4 / 7106
• HGNCID: 11859
• Length: 330
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 71/241 - (29%)
• Similarity: 124/241 - (51%)
• Gaps: 28/241 - (11%)

  Fly     1 MRSCGPS-----LIKYVLFAFNVLFAISGLGILIAGAVVLADVNEF----NHFVEGRVLAPPIVL 56
            ::.||.:     .:||::||||:||.:.|.|:|..|..:.|....|    :.|..   |:...:|
Human    88 LKRCGMARACLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPS---LSAANLL 149

  Fly    57 IVTGLIIFLIASLGCFGAIKESPTLLITFAVLLAVIFIVELAVGIAASVFKKDLEGMVKNSLQES 121
            |:||..:..|..:||.|||||:..||:||.:||.::|::|..:.|....:...::...:..|::.
Human   150 IITGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKG 214

  Fly   122 I----KRSNSEDTMAWDNIQQKLMCCGVDSPADWRTLSANKTLPGSCCQPQYIDSTVGHC-LESP 181
            :    .:.|...|.||..||....||||.:..||..:.....:|.|||. ::.:|    | |.:|
Human   215 LHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCCL-EFSES----CGLHAP 274

  Fly   182 ALGKDKYFQVGCVGKLKDRIEKNAIILIGV-GIGIAFIQILGIVLA 226
            .    .:::..|...:|..:::| ::.:|: |:..|.:||||:..|
Human   275 G----TWWKAPCYETVKVWLQEN-LLAVGIFGLCTALVQILGLTFA 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp47F	NP_725044.1	Tetraspanin	9..231	CDD:459767	69/228 (30%)
		tetraspanin_LEL	<134..205	CDD:351888	18/71 (25%)
TSPAN4	NP_001426622.1	None