Protein Alignment Tsp47F and Tspan15

DIOPT Version :10

• Sequence 1: NP_725044.1
• Gene: Tsp47F / 36230
• FlyBaseID: FBgn0033629
• Length: 239
• Species: Drosophila melanogaster
• Sequence 2: NP_001108504.1
• Gene: Tspan15 / 679462
• RGDID: 1588304
• Length: 294
• Species: Rattus norvegicus
• Alignment Length: 238
• Identity: 60/238 - (25%)
• Similarity: 113/238 - (47%)
• Gaps: 27/238 - (11%)

  Fly     9 IKYVLFAFNVLFAISGLGILIAGAVVLADVNEFNHFVEGRVLAPPIVLIVTGLIIFLIASLGCFG 73
            :|:.|..::.:|.:.|..:|..|....|:..::. .:|...|||.|:||:.|:::|:::.:|...
  Rat    20 LKFSLIIYSTVFWLIGGLVLSVGIYAEAERQKYK-TLESAFLAPAIILILLGVVMFIVSFIGVLA 83

  Fly    74 AIKESPTLLITFAVLLAVIFIVELAVGIAASVFKKDLEGMVKNSLQESIKRSNSEDTMAWDNI-- 136
            :::::..||.:|..:|.:..::||..||.|.:|:......:.::::..|:  |..|.:.:.||
  Rat    84 SLRDNLCLLQSFMFILGLCLVMELIGGIVALIFRNQTIDFLNDNIRRGIE--NYYDDLDFKNIMD 146

  Fly   137 --QQKLMCCGVDSPADWRTLSANK----TLPG--------SCCQPQYIDSTVGHC----LESPAL 183
              |:|..|||.:...||   |.|:    :.||        :||.....|.....|    ::...|
  Rat   147 FVQKKFKCCGGEDYRDW---SKNQYHDCSAPGPLACGVPYTCCIRNTTDVVNTMCGYKTIDKERL 208

  Fly   184 GKDKYFQV-GCVGKLKDRIEKNAIILIGVGIGIAFIQILGIVL 225
            .......| ||...:......|..|:.|:.:||...|.||::|
  Rat   209 NAQNIIHVRGCTNAVLIWFMDNYSIMAGLLLGILLPQFLGVLL 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp47F	NP_725044.1	Tetraspanin	9..231	CDD:459767	60/238 (25%)
		tetraspanin_LEL	<134..205	CDD:351888	21/91 (23%)
Tspan15	NP_001108504.1	Tetraspanin	20..>157	CDD:459767	36/139 (26%)
		penumbra_like_LEL	114..231	CDD:239411	25/121 (21%)