Protein Alignment Tsp47F and CD82

DIOPT Version :10

• Sequence 1: NP_725044.1
• Gene: Tsp47F / 36230
• FlyBaseID: FBgn0033629
• Length: 239
• Species: Drosophila melanogaster
• Sequence 2: XP_047282856.1
• Gene: CD82 / 3732
• HGNCID: 6210
• Length: 308
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 81/264 - (30%)
• Similarity: 132/264 - (50%)
• Gaps: 33/264 - (12%)

  Fly     1 MRSCGPSLIKYVLFAFNVLFAISGLGILIAGAVVLADVNEFNHFVE---GRVLAPPIVLIVTGLI 62
            |.|....:.||.||.||::|.|.|..||..|..:|||.:.|...::   ..:.....|.|..|.:
Human    42 MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFIGVGAV 106

  Fly    63 IFLIASLGCFGAIKESPTLLITFAVLLAVIFIVELAVGIAASVF-----KKDLEGMVKNSLQESI 122
            ..|:..|||.||:.|...||..:...|.:|.|.::..| |...|     |:::.|:|...:::
Human   107 TMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAG-ALFYFNMGKLKQEMGGIVTELIRD-- 168

  Fly   123 KRSNSEDTM--AWDNIQQKLMCCGVDSPADWRTLSA---NK---TLPGSCCQPQYIDSTV----G 175
            ..|:.||::  |||.:|.::.|||..|..:| |.:|   |:   |.|.||......|:::    |
Human   169 YNSSREDSLQDAWDYVQAQVKCCGWVSFYNW-TDNAELMNRPEVTYPCSCEVKGEEDNSLSVRKG 232

  Fly   176 HCLESPALGKDK--------YFQVGCVGKLKDRIEKNAIILIGVGIGIAFIQILGIVLACYLANS 232
            .| |:|......        .:|.||:.|::..:::|..|::|||:|:|.|::||:||:..|...
Human   233 FC-EAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELLGMVLSICLCRH 296

  Fly   233 IRQE 236
            :..|
Human   297 VHSE 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp47F	NP_725044.1	Tetraspanin	9..231	CDD:459767	78/249 (31%)
		tetraspanin_LEL	<134..205	CDD:351888	23/88 (26%)
CD82	XP_047282856.1	Tetraspanin	65..295	CDD:459767	70/234 (30%)
		CD37_CD82_like_LEL	147..270	CDD:239413	33/126 (26%)