Protein Alignment Tsp47F and TSPAN33

DIOPT Version :10

• Sequence 1: NP_725044.1
• Gene: Tsp47F / 36230
• FlyBaseID: FBgn0033629
• Length: 239
• Species: Drosophila melanogaster
• Sequence 2: NP_848657.1
• Gene: TSPAN33 / 340348
• HGNCID: 28743
• Length: 283
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 76/254 - (29%)
• Similarity: 125/254 - (49%)
• Gaps: 32/254 - (12%)

  Fly     8 LIKYVLFAFNVLFAISGLGILIAGAVVLADVNEFNHFVEGRVLAPPIVLIVTGLIIFLIASLGCF 72
            |:||:||.||:||.:..: :::|..|....:......:....:.|.|:|||.|:::||:...||.
Human    21 LVKYLLFFFNMLFWVISM-VMVAVGVYARLMKHAEAALACLAVDPAILLIVVGVLMFLLTFCGCI 84

  Fly    73 GAIKESPTLLITFAVLLAVIFIVELAVGIAASVFKKDLEGMVKNSLQESIKRSNSEDTMAWDNI- 136
            |:::|:..||.||::.|..:|:::||.||...||.....|.|...:..:|  .:..|.:...|:
Human    85 GSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAI--VHYRDDLDLQNLI 147

  Fly   137 ---QQKLMCCGVDSPADWRTLSANK--------------TLPGSCCQPQYIDSTVGHCLESPALG 184
               |:|..|||..|..||   |.|.              ::|.|||.|. .|..|.:.:....:.
Human   148 DFGQKKFSCCGGISYKDW---SQNMYFNCSEDNPSRERCSVPYSCCLPT-PDQAVINTMCGQGMQ 208

  Fly   185 KDKYFQV-------GCVGKLKDRIEKNAIILIGVGIGIAFIQILGIVLACYLANSIRQE 236
            ...|.:.       ||:.||.:.|..|..:|.||.:|:|..|::||:|:..|.|.|:.:
Human   209 AFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQILVNQIKDQ 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp47F	NP_725044.1	Tetraspanin	9..231	CDD:459767	73/246 (30%)
		tetraspanin_LEL	<134..205	CDD:351888	24/95 (25%)
TSPAN33	NP_848657.1	Tetraspanin	22..262	CDD:459767	73/246 (30%)
		penumbra_like_LEL	116..236	CDD:239411	30/125 (24%)