Protein Alignment Tsp47F and TSPAN17

DIOPT Version :10

• Sequence 1: NP_725044.1
• Gene: Tsp47F / 36230
• FlyBaseID: FBgn0033629
• Length: 239
• Species: Drosophila melanogaster
• Sequence 2: NP_001353420.1
• Gene: TSPAN17 / 26262
• HGNCID: 13594
• Length: 355
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 80/298 - (26%)
• Similarity: 124/298 - (41%)
• Gaps: 82/298 - (27%)

  Fly     4 CGPSLIKYVLFAFNVLFAISGLGILIAG------AVVLADVNEFNHFVEGRVLAPPIVLIVTGLI 62
            ||    ||.||.||::|.:.|...|..|      ..||::::.... :.|  |.|..:.:|.|.:
Human    16 CG----KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTD-LGG--LDPVWLFVVVGGV 73

  Fly    63 IFLIASLGCFGAIKESPTLLITFAVLLAVIFIVELAVGIAASVFKKDLEGMVKNSLQESIK--RS 125
            :.::...||.||::|:..||..|:|.|.:||.:|||.||.|.|||..:...:...:..::|  |.
Human    74 MSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAYRD 138

  Fly   126 NSEDTMAWDNIQQKLMCCGVDSPADWR-TLSANKT----------LPGSCCQPQYIDSTVGHCLE 179
            :.:.....|..|:...|||...|.||. .:..|.|          :|.||            |:.
Human   139 DIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSC------------CVR 191

  Fly   180 SPA-------LGKDKYFQV-----------GCVGKLKDRIEKNAIILIGVGIGIAF--------- 217
            .||       .|.|...::           ||||:.:..::.|.|::.||.:|||.
Human   192 DPAEDVLNTQCGYDVRLKLELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQVPLWPHV 256

  Fly   218 -----------------IQILGIVLACYLANSIRQERA 238
                             :||.||.||..|.:.|:..:|
Human   257 PLPLPGPPSLSPHLSSVLQIFGICLAQNLVSDIKAVKA 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp47F	NP_725044.1	Tetraspanin	9..231	CDD:459767	76/284 (27%)
		tetraspanin_LEL	<134..205	CDD:351888	22/99 (22%)
TSPAN17	NP_001353420.1	Tetraspanin	18..>157	CDD:459767	43/141 (30%)
		TM4SF9_like_LEL	115..235	CDD:239412	27/131 (21%)