Protein Alignment Tsp47F and TSPAN15

DIOPT Version :10

• Sequence 1: NP_725044.1
• Gene: Tsp47F / 36230
• FlyBaseID: FBgn0033629
• Length: 239
• Species: Drosophila melanogaster
• Sequence 2: NP_036471.1
• Gene: TSPAN15 / 23555
• HGNCID: 23298
• Length: 294
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 58/243 - (23%)
• Similarity: 118/243 - (48%)
• Gaps: 37/243 - (15%)

  Fly     9 IKYVLFAFNVLFAISGLGILIAGAVVLADVNEFNH-FVEGRVLAPPIVLIVTGLIIFLIASLGCF 72
            :|:.|..::.:|.:  :|.|:....:.|:|....: .:|...|||.|:||:.|:::|:::.:|..
Human    20 LKFSLIIYSTVFWL--IGALVLSVGIYAEVERQKYKTLESAFLAPAIILILLGVVMFMVSFIGVL 82

  Fly    73 GAIKESPTLLITFAVLLAVIFIVELAVGIAASVFKKDLEGMVKNSLQESIKRSNSEDTMAWDNI- 136
            .:::::..||..|..:|.:..|:||..|:.|..|:......:.::::..|:  |..|.:.:.||
Human    83 ASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIE--NYYDDLDFKNIM 145

  Fly   137 ---QQKLMCCGVDSPADWRTLSANK----TLPG--------SCC---QPQYIDSTVGHCLESPAL 183
               |:|..|||.:...||   |.|:    :.||        :||   ..:.:::..|:    ..:
Human   146 DFVQKKFKCCGGEDYRDW---SKNQYHDCSAPGPLACGVPYTCCIRNTTEVVNTMCGY----KTI 203

  Fly   184 GKDKY------FQVGCVGKLKDRIEKNAIILIGVGIGIAFIQILGIVL 225
            .|:::      :..||...:......|..|:.|:.:||...|.||::|
Human   204 DKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVLL 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp47F	NP_725044.1	Tetraspanin	9..231	CDD:459767	58/243 (24%)
		tetraspanin_LEL	<134..205	CDD:351888	19/95 (20%)
TSPAN15	NP_036471.1	Tetraspanin	20..>157	CDD:459767	36/140 (26%)
		penumbra_like_LEL	114..231	CDD:239411	23/125 (18%)