Protein Alignment Tsp47F and Tspan8

DIOPT Version :10

• Sequence 1: NP_725044.1
• Gene: Tsp47F / 36230
• FlyBaseID: FBgn0033629
• Length: 239
• Species: Drosophila melanogaster
• Sequence 2: NP_666122.1
• Gene: Tspan8 / 216350
• MGIID: 2384918
• Length: 235
• Species: Mus musculus
• Alignment Length: 244
• Identity: 72/244 - (29%)
• Similarity: 120/244 - (49%)
• Gaps: 42/244 - (17%)

  Fly     7 SLIKYVLFAFNVLFAISG---LGILI-------AGAVVLADVNEFNHFVEGRVLAPPIVLIVTGL 61
            |.:||.:|.||.||.:.|   ||:.|       ...::.:..:..|.|:...      :||..|.
Mouse     6 SCLKYSMFFFNFLFWVCGTLILGLAIWVRVSKDGKEIITSGDSSTNPFIAVN------ILIAVGS 64

  Fly    62 IIFLIASLGCFGAIKESPTLLITFAVLLAVIFIVELAVGIAASVFKKDLEGMVKNSLQESIK--R 124
            ||.::..|||.||:|||..:|:.|.:.|.:|.|:::|.||..:.||.:...::..:|.|:.|  .
Mouse    65 IIMVLGFLGCCGAVKESRCMLLLFFIGLLLILILQVAAGILGAAFKPEYNRILNETLYENAKLLS 129

  Fly   125 SNSEDTMAWDN----IQQKLMCCGVDS-PADW--RTLSANKT--LPGSCCQPQYIDSTVGHCLES 180
            .|:::...:..    .|.:..|||::: .|||  ..:.|.::  ..|:.| ..|..|:|
Mouse   130 DNTDEAKDFQKAMIVFQSEFKCCGLENGAADWGNNFVEAKESCQCTGTDC-ATYQGSSV------ 187

  Fly   181 PALGKDKYFQVGCVGKLKDRIEKNAIILIGVGIGIAFIQILGIVLACYL 229
                    :...|:..:||..|||.||:||:..|:|.|:|||:|.:..|
Mouse   188 --------YPKTCLSLIKDLFEKNIIIVIGIAFGLAVIEILGLVFSMVL 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp47F	NP_725044.1	Tetraspanin	9..231	CDD:459767	71/242 (29%)
		tetraspanin_LEL	<134..205	CDD:351888	18/79 (23%)
Tspan8	NP_666122.1	Tetraspanin	8..230	CDD:459767	71/242 (29%)
		TM4SF3_like_LEL	106..204	CDD:239407	24/112 (21%)