Protein Alignment Tsp47F and TSPAN19

DIOPT Version :10

• Sequence 1: NP_725044.1
• Gene: Tsp47F / 36230
• FlyBaseID: FBgn0033629
• Length: 239
• Species: Drosophila melanogaster
• Sequence 2: NP_001094387.1
• Gene: TSPAN19 / 144448
• HGNCID: 31886
• Length: 248
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 68/245 - (27%)
• Similarity: 103/245 - (42%)
• Gaps: 35/245 - (14%)

  Fly     8 LIKYVLFAFNVLFAISGLGILIAGAVVLADVNEF-------NHFVEGRVLAPPI--VLIVTGLII 63
            :|||.|...|..|.:.||..:..||.:|.|.|.|       |||:      .||  :||..|...
Human     9 IIKYFLNLINGAFLVLGLLFMGFGAWLLLDRNNFLTAFDENNHFI------VPISQILIGMGSST 67

  Fly    64 FLIASLGCFGAIKESPTLLITFAVLLAVIFIVELAVGIAASVFKKDLEGMVKNSLQESIKRSNS- 127
            .|...||..|...|...|||.:|||:...|.|::.:.......|::::.:..:.:...|....|
Human    68 VLFCLLGYIGIHNEIRWLLIVYAVLITWTFAVQVVLSAFIITKKEEVQQLWHDKIDFVISEYGSK 132

  Fly   128 ---EDTMAW---DNIQQKLMCCGVDSPADWRTLSANK----TLPGSCCQPQYIDSTVGHCLESPA 182
               ||...|   :.:|:.|.|||..:..|| ..:.||    .:|.||.:     ||:........
Human   133 DKPEDITKWTILNALQKTLQCCGQHNYTDW-IKNKNKENSGQVPCSCTK-----STLRKWFCDEP 191

  Fly   183 LGKDKYFQVGCVGKLKDRIEKNAIILIGVGIGIAFIQILGIVL-ACYLAN 231
            |.. .|.: ||..|:......|.:.|||:..|:...::..:.| .|:..|
Human   192 LNA-TYLE-GCENKISAWYNVNVLTLIGINFGLLTSEVFQVSLTVCFFKN 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp47F	NP_725044.1	Tetraspanin	9..231	CDD:459767	67/242 (28%)
		tetraspanin_LEL	<134..205	CDD:351888	19/74 (26%)
TSPAN19	NP_001094387.1	Tetraspanin	10..>155	CDD:459767	44/150 (29%)
		CD37_CD82_like_LEL	107..212	CDD:239413	25/112 (22%)