Protein Alignment Tsp47F and TSPAN2

DIOPT Version :10

• Sequence 1: NP_725044.1
• Gene: Tsp47F / 36230
• FlyBaseID: FBgn0033629
• Length: 239
• Species: Drosophila melanogaster
• Sequence 2: NP_005716.2
• Gene: TSPAN2 / 10100
• HGNCID: 20659
• Length: 221
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 62/248 - (25%)
• Similarity: 104/248 - (41%)
• Gaps: 51/248 - (20%)

  Fly     5 GPSLIKYVLFAFNVLFAISGLGIL-------IAGAV--VLADVNEFNHFVEGRVLAPPIVLIVTG 60
            |...|||:|..||:||.::|..::       ..||:  :.::.....:|..|.     .||:..|
Human     7 GLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGL-----YVLVGAG 66

  Fly    61 LIIFLIASLGCFGAIKESPTLLITFAVLLAVIFIVELAVGIAASVFK----KDLEGMVKNSLQES 121
            .::..:...||.||::||..:|.:|...|.|||..|:..|:.|.:.|    :.::.|.:.:..:.
Human    67 ALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAYNDY 131

  Fly   122 IK-RSNSEDTMAWDNIQQKLMCCGVDSPADWRTLSANKTLPGSCCQPQYIDSTVGHCLESPALGK 185
            :| |.....|:.  .......|||.:|...              .||......:||
Human   132 LKDRGKGNGTLI--TFHSTFQCCGKESSEQ--------------VQPTCPKELLGH--------- 171

  Fly   186 DKYFQVGCVGKLKDRIEKNAIILIG-VGIGIAFIQILGIVLACYLANSIRQER 237
                 ..|:.:::..|... :.||| ||||||.:.|.|::.:..|..:||..|
Human   172 -----KNCIDEIETIISVK-LQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSR 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp47F	NP_725044.1	Tetraspanin	9..231	CDD:459767	58/236 (25%)
		tetraspanin_LEL	<134..205	CDD:351888	10/70 (14%)
TSPAN2	NP_005716.2	Tetraspanin	11..212	CDD:459767	58/236 (25%)
		CD81_like_LEL	110..186	CDD:239404	15/106 (14%)