Protein Alignment Tsp47F and TSPAN3

DIOPT Version :10

• Sequence 1: NP_725044.1
• Gene: Tsp47F / 36230
• FlyBaseID: FBgn0033629
• Length: 239
• Species: Drosophila melanogaster
• Sequence 2: NP_005715.1
• Gene: TSPAN3 / 10099
• HGNCID: 17752
• Length: 253
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 73/238 - (30%)
• Similarity: 125/238 - (52%)
• Gaps: 18/238 - (7%)

  Fly     1 MRSCGPSLIKYVLFAFNVLFAISGLGIL-IAGAVVLADVNEFNHFVEG-RVLAPPIVLIVTGLII 63
            |..||.:..|.||...|::| ....||| ..||.|....::::||.|. ..|.|.:|:|..|.::
Human     1 MGQCGITSSKTVLVFLNLIF-WGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALL 64

  Fly    64 FLIASLGCFGAIKESPTLLITFAVLLAVIFIVELAVGIAASVFKKDLEGMVKNSLQESIKRSNSE 128
            |:|..:||...|:||...|.||.::|.::|:.|:.|.:...|::..:|..|..|:|:..|..|..
Human    65 FIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGT 129

  Fly   129 D----TMAWDNIQQKLMCCGVDSPADWRTL-----SANKTLPGSCCQPQYIDSTVGHCLESPALG 184
            :    :.|.|.:|::|.|||:.:.:||...     :.|:::|.|||:     .|..:|..|.|..
Human   130 NPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCR-----ETASNCNGSLAHP 189

  Fly   185 KDKYFQVGCVGKLKDRIEKNAIILIGVGIGIAFIQILGIVLAC 227
            .|.|.: ||...:..::::..:.:|...:..|.||:||::.||
Human   190 SDLYAE-GCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCAC 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp47F	NP_725044.1	Tetraspanin	9..231	CDD:459767	70/230 (30%)
		tetraspanin_LEL	<134..205	CDD:351888	21/75 (28%)
TSPAN3	NP_005715.1	Tetraspanin	9..235	CDD:459767	70/230 (30%)
		TM4SF8_like_LEL	104..210	CDD:239416	29/111 (26%)