Protein Alignment Tsp47F and TSPAN5

DIOPT Version :10

• Sequence 1: NP_725044.1
• Gene: Tsp47F / 36230
• FlyBaseID: FBgn0033629
• Length: 239
• Species: Drosophila melanogaster
• Sequence 2: NP_005714.2
• Gene: TSPAN5 / 10098
• HGNCID: 17753
• Length: 268
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 77/268 - (28%)
• Similarity: 126/268 - (47%)
• Gaps: 43/268 - (16%)

  Fly     5 GPSL---IKYVLFAFNVLF---AISGLGI---------LIAGAVVLADVNEFNHFVEGRVLAPPI 54
            ||.:   |||.:|.|||:|   .|:.|||         :::....:.|:..|:         |..
Human     8 GPEVSCCIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDLGGFD---------PVW 63

  Fly    55 VLIVTGLIIFLIASLGCFGAIKESPTLLITFAVLLAVIFIVELAVGIAASVFKKDLEGMVKNSLQ 119
            :.:|.|.::|::...||.||::|:..||..|:|.|.:||.:||..|:.|.|||..::..:...:.
Human    64 LFLVVGGVMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKDWIKDQLYFFIN 128

  Fly   120 ESIK--RSNSEDTMAWDNIQQKLMCCGVDSPADWR-TLSANKT----------LPGSCC----QP 167
            .:|:  |.:.:.....|..|:...|||.....||. .:..|.|          :|.|||    ..
Human   129 NNIRAYRDDIDLQNLIDFTQEYWQCCGAFGADDWNLNIYFNCTDSNASRERCGVPFSCCTKDPAE 193

  Fly   168 QYIDSTVGH-CLESPALGKD-KYFQVGCVGKLKDRIEKNAIILIGVGIGIAFIQILGIVLACYLA 230
            ..|::..|: ..:.|.:.:. ..:..|||.:.:..::.|..|:.|:.||||.:||.||.||..|.
Human   194 DVINTQCGYDARQKPEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIFIGIALLQIFGICLAQNLV 258

  Fly   231 NSIRQERA 238
            :.|...||
Human   259 SDIEAVRA 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp47F	NP_725044.1	Tetraspanin	9..231	CDD:459767	72/252 (29%)
		tetraspanin_LEL	<134..205	CDD:351888	19/87 (22%)
TSPAN5	NP_005714.2	Tetraspanin	15..258	CDD:459767	71/251 (28%)
		TM4SF9_like_LEL	113..233	CDD:239412	24/119 (20%)