Protein Alignment iotaTry and TMPRSS13

DIOPT Version :10

• Sequence 1: NP_523695.1
• Gene: iotaTry / 36223
• FlyBaseID: FBgn0015001
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_001070731.1
• Gene: TMPRSS13 / 84000
• HGNCID: 29808
• Length: 567
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 80/237 - (33%)
• Similarity: 113/237 - (47%)
• Gaps: 21/237 - (8%)

  Fly    25 TGRIIGGSDQLIRNAPWQVSIQISARHECGGVIYSKEIIITAGHCL---HERSVTLMKVRVGAQN 86
            ||||:||:.......|||||:.....|.|||.:...:.::||.||.   .|:.:...||..|..|
Human   323 TGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSN 387

  Fly    87 HNYGGTLVPVAAYKVHEQFDSRFLHYDIAVLRLSTPLTFGLSTRAINLASTSPSGGT-----TVT 146
            .:.......:|...::..:......||||::|||.|||  ||.. |:.|.....|.|     |..
Human   388 LHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLT--LSAH-IHPACLPMHGQTFSLNETCW 449

  Fly   147 VTGWGHT--DNGALSDSLQKAQLQIIDRGECASQKFGYGADFVGEETICAAST--DADACTGDSG 207
            :||:|.|  .:...|..|::.|:.:||..:| :....|.: ::....:||...  ..|:|.||||
Human   450 ITGFGKTRETDDKTSPFLREVQVNLIDFKKC-NDYLVYDS-YLTPRMMCAGDLRGGRDSCQGDSG 512

  Fly   208 GPLVASSQ----LVGIVSWGYRCADDNYPGVYADVAILRPWI 245
            ||||....    |.|:.|||..|...|.||||..|..:.|||
Human   513 GPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWI 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
iotaTry	NP_523695.1	Tryp_SPc	27..245	CDD:214473	76/233 (33%)
TMPRSS13	NP_001070731.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..115
		PHA03378	<9..148	CDD:223065
		13 X 5 AA repeats of A-S-P-A-[GLQR]	9..93
		4 X 5 AA repeats of T-P-P-G-R	14..68
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	131..157
		SRCR_2	231..321	CDD:464747
		Tryp_SPc	325..554	CDD:214473	76/233 (33%)