Protein Alignment iotaTry and TPSAB1

DIOPT Version :10

• Sequence 1: NP_523695.1
• Gene: iotaTry / 36223
• FlyBaseID: FBgn0015001
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_003285.2
• Gene: TPSAB1 / 7177
• HGNCID: 12019
• Length: 275
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 78/242 - (32%)
• Similarity: 117/242 - (48%)
• Gaps: 29/242 - (11%)

  Fly    28 IIGGSDQLIRNAPWQVSIQISA---RHECGGVIYSKEIIITAGHCL--HERSVTLMKVRVGAQNH 87
            |:||.:......|||||:::..   .|.|||.:...:.::||.||:  ..:.:..::|::..|:.
Human    31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHL 95

  Fly    88 NYGGTLVPVAAYKVHEQFDSRFLHYDIAVLRLSTPLTFGLSTRAINL--ASTSPSGGTTVTVTGW 150
            .|...|:||:...||.||.:..:..|||:|.|..|:........:.|  ||.:...|....||||
Human    96 YYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGW 160

  Fly   151 GHTDNGALSDS-------LQKAQLQIIDRGECASQKFGYGA------DFVGEETICAASTDADAC 202
            |..||    |.       |::.::.|::...| ..|:..||      ..|.::.:||.:|..|:|
Human   161 GDVDN----DERLPPPFPLKQVKVPIMENHIC-DAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSC 220

  Fly   203 TGDSGGPLVASSQ----LVGIVSWGYRCADDNYPGVYADVAILRPWI 245
            .||||||||....    ..|:||||..||..|.||:|..|.....||
Human   221 QGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWI 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
iotaTry	NP_523695.1	Tryp_SPc	27..245	CDD:214473	76/240 (32%)
TPSAB1	NP_003285.2	Tryp_SPc	31..268	CDD:238113	78/242 (32%)