Protein Alignment iotaTry and PRSS22

DIOPT Version :10

• Sequence 1: NP_523695.1
• Gene: iotaTry / 36223
• FlyBaseID: FBgn0015001
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 82/246 - (33%)
• Similarity: 116/246 - (47%)
• Gaps: 22/246 - (8%)

  Fly    27 RIIGGSDQLIRNAPWQVSIQISARHECGGVIYSKEIIITAGHCLHE--RSVTLMKVRVGA-QNHN 88
            |::||.|......||.||||.:..|.|.|.:.:...:|||.||..:  ....|..|.:|| |..|
Human   157 RVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGN 221

  Fly    89 YG--GTLVPVAAYKVHEQFD-SRFLHYDIAVLRLSTPLTFGLSTRAINL----ASTSPSGGTTVT 146
            .|  ...|.||..:.|..:. ......|||::||...:.|  |.|.:.:    ||......|...
Human   222 PGSRSQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQF--SERVLPICLPDASIHLPPNTHCW 284

  Fly   147 VTGWGHTDNGA---LSDSLQKAQLQIIDRGECASQKF-GYGADFVGEETICAA--STDADACTGD 205
            ::|||...:|.   ...:|||.::.|||...|:...: |.|...:.|:.:||.  ..:.|||.||
Human   285 ISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDACLGD 349

  Fly   206 SGGPLVASSQ----LVGIVSWGYRCADDNYPGVYADVAILRPWIVKAANAI 252
            |||||:....    |.||:|||..||:.|.||||..::..|.|:.|....:
Human   350 SGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGV 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
iotaTry	NP_523695.1	Tryp_SPc	27..245	CDD:214473	80/237 (34%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	80/239 (33%)