DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment iotaTry and Prss53

DIOPT Version :9

Sequence 1:	NP_523695.1	Gene:	iotaTry / 36223	FlyBaseID:	FBgn0015001	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	260	Identity:	63/260 - (24%)
Similarity:	97/260 - (37%)	Gaps:	56/260 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LGDASDVEATGRIIGGSDQ--LIRNAPWQVSIQISARHECGGVIYSKEIIITAGHC------LHE 72
            :.|.:...|.|.:..|..|  .:...||...::...:..|||.:.|:.:::||.||      |.|
  Rat   326 MSDENSCVACGSLSSGGPQAGALSQWPWDARLKHHGKLACGGALVSEVVVLTAAHCFIGRQTLEE 390

  Fly    73 RSVTL--------MKVRV--GAQNHNYGGTLVPVAAYKVHEQFDSRFLHYDIAVLRLSTPLTFGL 127
            .||.|        :|..:  ||..|..||                    :|:|.|.|:.|:|.|.
  Rat   391 WSVGLGAGPEEWGLKQLILHGAYTHPEGG--------------------HDVAFLLLAQPVTLGP 435

  Fly   128 STRAINLASTS---PSGGTTVTVTGW--GHTDNGALSDSLQKAQLQIIDRGECASQKFGYGADFV 187
            ..|.:.|....   |.|     ..||  |.|....::.. ....:.::....|:.|....|:..|
  Rat   436 GLRPLCLPYADHRLPDG-----EHGWVLGLTREAGINHP-HTVPVTVLGPMACSRQHAASGSTGV 494

  Fly   188 G--EETICAAST-DADACTGDSGGPLVASSQ----LVGIVSWGYRCADDNYPGVYADVAILRPWI 245
            .  ...||.... :...|.|.||.|||...:    |.|:.|:|..|.....|.|:|.::....|:
  Rat   495 PILPGMICTTVVGEPPHCEGLSGAPLVHEIRGTWFLAGLHSFGDTCQGSAKPAVFAALSAYEDWV 559

Fly 246 245
Rat 560 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
iotaTry	NP_523695.1	Tryp_SPc	27..245	CDD:214473	59/247 (24%)
iotaTry	NP_523695.1	Tryp_SPc	28..247	CDD:238113	60/248 (24%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113	60/245 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343322
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030