DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment iotaTry and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_523695.1	Gene:	iotaTry / 36223	FlyBaseID:	FBgn0015001	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_001003979.1	Gene:	Tmprss11c / 408213	RGDID:	1302967	Length:	418	Species:	Rattus norvegicus

Alignment Length:	258	Identity:	90/258 - (34%)
Similarity:	122/258 - (47%)	Gaps:	35/258 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LLGDASDVEATG-----------RIIGGSDQLIRNAPWQVSIQISARHECGGVIYSKEIIITAGH 68
            ||.|:|..:.:|           ::.||.|......|||.|:|.:..|.||..:.|...:|||.|
  Rat   163 LLIDSSSFKFSGCGRRTITPGGHKVAGGQDAEEGEWPWQASLQQNNVHRCGATLISNSWLITAAH 227

  Fly    69 CLHERSVTLMKVRVGAQNHNYGGTLVPVAAYK------VHEQFDSRFLHYDIAVLRLSTPLTFGL 127
            |. .||......:|     ::|..|....|.:      :||.:.....:.||||:|||:|:.:..
  Rat   228 CF-VRSANPKDWKV-----SFGFLLSKPQAQRAVKSIVIHENYSYPAHNNDIAVVRLSSPVLYEN 286

  Fly   128 STRAINL--ASTSPSGGTTVTVTGWGH-TDNGALSDSLQKAQLQIIDRGECASQKFGYGADFVGE 189
            :.|...|  |:......:.|.|||||. ..:|...:.|||.:::|||...|.|.| .||. .:..
  Rat   287 NIRRACLPEATQKFPPNSDVVVTGWGTLKSDGDSPNILQKGRVKIIDNKTCNSGK-AYGG-VITP 349

  Fly   190 ETICAASTD--ADACTGDSGGPLVASSQ-----LVGIVSWGYRCADDNYPGVYADVAILRPWI 245
            ..:||...:  .|||.||||||||:...     |.||||||..||..|.||||..|...|.||
  Rat   350 GMLCAGFLEGRVDACQGDSGGPLVSEDSKGIWFLAGIVSWGDECALPNKPGVYTRVTHYRDWI 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
iotaTry	NP_523695.1	Tryp_SPc	27..245	CDD:214473	83/233 (36%)
iotaTry	NP_523695.1	Tryp_SPc	28..247	CDD:238113	85/234 (36%)
Tmprss11c	NP_001003979.1	SEA	62..157	CDD:279699
		Tryp_SPc	186..412	CDD:214473	83/233 (36%)
		Tryp_SPc	187..415	CDD:238113	85/234 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920