Protein Alignment iotaTry and PRSS57

DIOPT Version :10

• Sequence 1: NP_523695.1
• Gene: iotaTry / 36223
• FlyBaseID: FBgn0015001
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_999875.2
• Gene: PRSS57 / 400668
• HGNCID: 31397
• Length: 283
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 73/253 - (28%)
• Similarity: 113/253 - (44%)
• Gaps: 23/253 - (9%)

  Fly     7 VATVLVLLLLGDASDVEATGRIIGGSDQLIRNAPWQVSIQISARHECGGVIYSKEIIITAGHCLH 71
            |||.|:|.:...|....|  :||||.:....:.|:..|::...:|.|||.:.....:::|.||..
Human    15 VATALMLPVKPPAGSWGA--QIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFS 77

  Fly    72 ERSVTLMKVRVGAQNHNYGGTLVP------VAAYKVHEQFDSRFLHYDIAVLRLSTPLTFGLST- 129
            .|.:....|.:||   :...|..|      :.|...|..:.......||.:|||:.....|.:.
Human    78 HRDLRTGLVVLGA---HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVG 139

  Fly   130 --RAINLASTSPSGGTTVTVTGWGH-TDNGALSDSLQKAQLQIIDRGECASQKFGYGADFVGEET 191
              |.....:..|:.||...|.|||. :|...|...|.:|:::::|...|.|...|:    :....
Human   140 LLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH----LTLTM 200

  Fly   192 ICAASTDADA---CTGDSGGPLVASSQLVGIVSW-GYRCADDNYPGVYADVAILRPWI 245
            :|..|.|:..   |:.|||||||..::..|:||: |..|.|...|.||..|:....||
Human   201 LCTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
iotaTry	NP_523695.1	Tryp_SPc	27..245	CDD:214473	64/231 (28%)
PRSS57	NP_999875.2	Tryp_SPc	34..258	CDD:238113	64/230 (28%)